%0 Journal Article %1 gotz2018triazolebased %A Götz, Tobias %A Schädel, Nicole %A Petri, Nadja %A Kirchhof, Manuel %A Bilitewski, Ursula %A Tovar, Günter E. M. %A Laschat, Sabine %A Southan, Alexander %D 2018 %J RSC Advances 2018 %K oafonds %N (34743) %R doi:10.1039/C8RA07145D %T Triazole-based cross-linkers in radical polymerization processes: tuning mechanical properties of poly(acrylamide) and poly(N,N-dimethylacrylamide) hydrogels %V 60 %X Triazole-based cross-linkers with different spacer lengths and different functional end groups (acrylamides, methacrylamides, maleimides and vinylsulfonamides) were synthesized, investigated for cytotoxic and antibacterial activity, and incorporated into poly(acrylamide) (PAAm) and poly(N,N-dimethylacrylamide) (PDMAAm) hydrogels by free-radical polymerization. Hydrogels prepared with different cross-linkers and cross-linker contents between 0.2% and 1.0% were compared by gel yields, equilibrium degrees of swelling (S) and storage moduli (G′). Generally with increasing cross-linker content, G′ values of the hydrogels increased, while S values decreased. The different polymerizable cross-linker end groups resulted in a decrease of G′ in the following order for cross-linkers with C4 spacers: acrylamide > maleimide > methacrylamide > vinylsulfonamide. Longer cross-linker alkyl spacer lengths caused an increase in G′ and a decrease in S. Independent of the cross-linker used, a universal correlation between G′ and equilibrium polymer volume fraction ϕ was found. For PAAm hydrogels, G′ ranged between 4 kPa and 23 kPa and ϕ between 0.07 and 0.14. For PDMAAm hydrogels, G′ ranged between 0.1 kPa and 4.9 kPa and ϕ between 0.02 and 0.06. The collected data were used to establish an empirical model to predict G′ depending on ϕ. G′ of PAAm and PDMAAm hydrogels is given by G′ = 4034 kPa ϕ2.66 and G′ = 4297 kPa ϕ2.46, respectively.

@article{gotz2018triazolebased, abstract = {Triazole-based cross-linkers with different spacer lengths and different functional end groups (acrylamides, methacrylamides, maleimides and vinylsulfonamides) were synthesized, investigated for cytotoxic and antibacterial activity, and incorporated into poly(acrylamide) (PAAm) and poly(N,N-dimethylacrylamide) (PDMAAm) hydrogels by free-radical polymerization. Hydrogels prepared with different cross-linkers and cross-linker contents between 0.2% and 1.0% were compared by gel yields, equilibrium degrees of swelling (S) and storage moduli (G′). Generally with increasing cross-linker content, G′ values of the hydrogels increased, while S values decreased. The different polymerizable cross-linker end groups resulted in a decrease of G′ in the following order for cross-linkers with C4 spacers: acrylamide > maleimide > methacrylamide > vinylsulfonamide. Longer cross-linker alkyl spacer lengths caused an increase in G′ and a decrease in S. Independent of the cross-linker used, a universal correlation between G′ and equilibrium polymer volume fraction ϕ was found. For PAAm hydrogels, G′ ranged between 4 kPa and 23 kPa and ϕ between 0.07 and 0.14. For PDMAAm hydrogels, G′ ranged between 0.1 kPa and 4.9 kPa and ϕ between 0.02 and 0.06. The collected data were used to establish an empirical model to predict G′ depending on ϕ. G′ of PAAm and PDMAAm hydrogels is given by G′ = 4034 kPa ϕ2.66 and G′ = 4297 kPa ϕ2.46, respectively.}, added-at = {2019-02-07T15:22:06.000+0100}, author = {Götz, Tobias and Schädel, Nicole and Petri, Nadja and Kirchhof, Manuel and Bilitewski, Ursula and Tovar, Günter E. M. and Laschat, Sabine and Southan, Alexander}, biburl = {https://puma.ub.uni-stuttgart.de/bibtex/29eee64f4ad4949f5425de17f386ea366/ninawittmann}, doi = {doi:10.1039/C8RA07145D}, interhash = {ce170e32d54b7e1a6b5337b3cd193edb}, intrahash = {9eee64f4ad4949f5425de17f386ea366}, journal = {RSC Advances 2018}, keywords = {oafonds}, number = {(34743)}, timestamp = {2019-02-07T14:22:06.000+0100}, title = {Triazole-based cross-linkers in radical polymerization processes: tuning mechanical properties of poly(acrylamide) and poly(N,N-dimethylacrylamide) hydrogels}, volume = 60, year = 2018 }