%0 Generic %1 werneck2023through %A Werneck, Linda %A Yildiz, Erdost %A Han, Mertcan %A Keip, Marc-Andre %A Sitti, Metin %A Ortiz, Michael %D 2023 %K unclear PN3 PN3-5(II) EXC2075 darus %R 10.18419/darus-3575 %T Ion Flow Through Neural Ion Membrane: scripts and data %X The scripts and data are related to the numerical implementation of a quantitative model for ion flow through neural ion channels and a validation of the underlying single ion channel flow model for gramicidin A channels. The model is based on the Poisson-Nernst-Planck (PNP) equations for ion transport and is described in the related publication in detail. Gramicidin A:A PNP based model for ion flow through single ion channels is established. We validate our results with experimental data by Busath et al. [1998] (files "NaCl.xlsx" and "KCl.xlsx") for gramicidin A channels with NaCl and KCl solutions of different concentrations.Quantitative Model: We extend the single channel model by calibrating it with whole-cell patch clamp in-house experimental data (file "DataPatchClampIV.xlsx"). We refer to the related publication for information on the experimental setup.See comments in the scripts for further information.

@misc{werneck2023through, abstract = {The scripts and data are related to the numerical implementation of a quantitative model for ion flow through neural ion channels and a validation of the underlying single ion channel flow model for gramicidin A channels. The model is based on the Poisson-Nernst-Planck (PNP) equations for ion transport and is described in the related publication in detail. Gramicidin A:A PNP based model for ion flow through single ion channels is established. We validate our results with experimental data by Busath et al. [1998] (files "NaCl.xlsx" and "KCl.xlsx") for gramicidin A channels with NaCl and KCl solutions of different concentrations.Quantitative Model: We extend the single channel model by calibrating it with whole-cell patch clamp in-house experimental data (file "DataPatchClampIV.xlsx"). We refer to the related publication for information on the experimental setup.See comments in the scripts for further information. }, added-at = {2024-09-18T13:43:03.000+0200}, affiliation = {Werneck, Linda/Institute of Applied Mechanics, University of Stuttgart, Yildiz, Erdost/Physical Intelligence Department, Max Planck Institute for Intelligent Systems, Han, Mertcan/Physical Intelligence Department, Max Planck Institute for Intelligent Systems, Keip, Marc-Andre/Institute of Applied Mechanics, University of Stuttgart, Sitti, Metin/Institute for Biomedical Engineering, ETH Zurich, Ortiz, Michael/Division of Engineering and Applied Science, California Institute of Technology}, author = {Werneck, Linda and Yildiz, Erdost and Han, Mertcan and Keip, Marc-Andre and Sitti, Metin and Ortiz, Michael}, biburl = {https://puma.ub.uni-stuttgart.de/bibtex/21dad6dd6ed313a912a27b07e0d8c1fec/exc2075}, doi = {10.18419/darus-3575}, howpublished = {Software}, interhash = {dde20d053cf60b738116a46af9e14bcb}, intrahash = {1dad6dd6ed313a912a27b07e0d8c1fec}, keywords = {unclear PN3 PN3-5(II) EXC2075 darus}, note = {Related to: Werneck, L., Han, M., Yildiz, E., Keip, M.-A., Sitti, M., & Ortiz, M. (2023). A Simple Quantitative Model of Neuromodulation, Part I: Ion Flow Through Neural Ion Channels. Journal of the Mechanics and Physics of Solids, 182:105457. doi: 10.1016/j.jmps.2023.105457}, orcid-numbers = {Werneck, Linda/0009-0004-1227-6351, Yildiz, Erdost/0000-0001-8086-3524, Han, Mertcan/0000-0002-3543-5894, Keip, Marc-Andre/0000-0002-5838-5201, Sitti, Metin/0000-0001-8249-3854, Ortiz, Michael/0000-0001-5877-4824}, timestamp = {2024-10-07T09:24:08.000+0200}, title = {Ion Flow Through Neural Ion Membrane: scripts and data}, year = 2023 }