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Quantifying fat zonation in liver lobules: an integrated multiscale in silico model combining disturbed microperfusion and fat metabolism via a continuum biomechanical bi-scale, tri-phasic approach

L. Lambers, N. Waschinsky, J. Schleicher, M. König, H. Tautenhahn, M. Albadry, U. Dahmen, and T. Ricken. Biomechanics and Modeling in Mechanobiology, (2024)
DOI: 10.1007/s10237-023-01797-0

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Uta Bösch University of Stuttgart

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A fast and robust hepatocyte quantification algorithm including vein processing.T. Ivanovska, A. Schenk, A. Homeyer, M. Deng, U. Dahmen, O. Dirsch, H. Hahn, and L. Linsen. BMC Bioinformatics, (2010)Practical quantification of necrosis in histological whole-slide images.A. Homeyer, A. Schenk, J. Arlt, U. Dahmen, O. Dirsch, and H. Hahn. Comp. Med. Imag. and Graph., 37 (4): 313-322 (2013)Vollautomatische Vorverarbeitung und rigide Registrierung zur Rekonstruktion von Bildern histologischer Stufenschnitte der Rattenleber.A. Weinhold, S. Wirtz, A. Schenk, T. Böhler, X. Jiang, U. Dahmen, O. Dirsch, and H. Peitgen. Bildverarbeitung für die Medizin, page 419-423. Springer, (2007)A Biphasic FEM Model for the Microperfusion in Liver LobulesD. Werner, T. Ricken, U. Dahmen, and O. Dirsch. PAMM, 12 (1): 89--90 (2012)Hepatectomy-Induced Alterations in Hepatic Perfusion and Function - Toward Multi-Scale Computational Modeling for a Better Prediction of Post-hepatectomy Liver FunctionB. Christ, M. Collatz, U. Dahmen, K. Herrmann, S. Höpfl, M. König, L. Lambers, M. Marz, D. Meyer, N. Radde and 3 other author(s). Frontiers in Physiology, (2021)On a Tri--Scale and Multiphase Model for the Description of Perfusion coupled to Fat Growth Effects in Liver TissueN. Waschinsky, D. Werner, T. Ricken, U. Dahmen, and O. Dirsch. PAMM, 17 (1): 227--228 (2018)A Biphasic 3D-FEM model for the remodeling of microcirculation in liver lobesT. Ricken, U. Dahmen, O. Dirsch, and D. Werner. Computer Models in Biomechanics, Springer, (2013)Limited Correlation Between Conventional Pathologist and Automatic Computer-Assisted Quantification of Hepatic Steatosis due to Difference Between Event-Based and Surface-Based Analysis.M. Deng, U. Dahmen, J. Sun, H. Huang, C. Sehestedt, A. Homeyer, A. Schenk, and O. Dirsch. IEEE J. Biomedical and Health Informatics, 18 (4): 1473-1477 (2014)On a bi-scale and tri-phasic model for the description of growth in biological tissue using the example of the human liverN. Waschinsky, D. Werner, T. Ricken, U. Dahmen, and O. Dirsch. PAMM, 16 (1): 109--110 (2016)On the Influence of Growth in Perfusion Dependent Biological Systems - at the Example of the Human LiverD. Werner, T. Ricken, U. Dahmen, O. Dirsch, H. Holzhütter, and M. König. PAMM, 15 (1): 119--120 (2015)

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Uta Bösch University of Stuttgart

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