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Additional data related to Khella et al.: The T1150A cancer mutant of the protein lysine methyltransferase NSD2 can introduce H3K36 trimethylation

, , , , , and . Software, (2023)Related to: Mina S. Khella, Philipp Schnee, Sara Weirich, Tan Bui, Alexander Bröhm, Pavel Bashtrykov, Jürgen Pleiss, Albert Jeltsch: The T1150A cancer mutant of the protein lysine methyltransferase NSD2 can introduce H3K36 trimethylation. J Biol Chem, 2023, 5, 104796. doi: 10.1016/j.jbc.2023.104796.
DOI: 10.18419/darus-3263

Abstract

This data collection contains additional data related to Khellaet al.: "The T1150A cancer mutant of the protein lysine methyltransferase NSD2 can introduce H3K36 trimethylation". This includes Movie 1: Example of a successful docking of AdoMet to the NSD2 T1150A - H3K36me2 peptide complex, Modelled structures of NSD2 bound to different peptides and cofactors, Source data of the results of the MD analysis, MD simulations codes and analysis scripts, Supplementary Tables

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