%0 Conference Proceedings %1 Rall.1997 %D 1997 %E Rall, Jochen %E Waldhor, Eberhard %E Schwederski, Brigitte %E Schwach, Manuela %E Kohlmann, Stephan %E Kaim, Wolfgang. %I Wiley-VCH Verlag GmbH %K amine benzoquinone copper methylthiomethylbenzimidazole methylthiomethylbenzimidazole;copper model oxidase prepn quinone tautomerism;review valence %T Synthetic and spectroscopic approaches to the copper/quinone-coupled center in amine oxidases: Bioinorg. Chem %X The interaction between the metal and the potentially o- or p-quinonoid topaquinone (TPQ) ligand in the active site of Cu-dependent amine oxidases was approached using (Qn-)Cun+(L), Q = 3,5-di-tert-butyl-o-benzoquinone and L = 1-alkyl-2-(methylthiomethyl)-1H-benzimidazole, as a first model system for the enzymically relevant and EPR-detectable valence tautomerism (n = 1 or 2). The data are preceded by a review of model systems related to the function and coupling of Cu metal and the org. cofactor in copper-dependent amine oxidases, including the use of 2,4,5-trihydroxytoluene as a model for TPQ. on SciFinder(R)

@proceedings{Rall.1997, abstract = {The interaction between the metal and the potentially o- or p-quinonoid topaquinone (TPQ) ligand in the active site of Cu-dependent amine oxidases was approached using (Qn-)Cun+(L), Q = 3,5-di-tert-butyl-o-benzoquinone and L = 1-alkyl-2-(methylthiomethyl)-1H-benzimidazole, as a first model system for the enzymically relevant and EPR-detectable valence tautomerism (n = 1 or 2). The data are preceded by a review of model systems related to the function and coupling of Cu metal and the org. cofactor in copper-dependent amine oxidases, including the use of 2,4,5-trihydroxytoluene as a model for TPQ. [on SciFinder(R)]}, added-at = {2022-06-15T11:26:56.000+0200}, biburl = {https://puma.ub.uni-stuttgart.de/bibtex/2d5878964f65d884a81264059d7f2b2a2/huebleriac}, editor = {Rall, Jochen and Waldhor, Eberhard and Schwederski, Brigitte and Schwach, Manuela and Kohlmann, Stephan and Kaim, Wolfgang.}, interhash = {6de770c5601250d356e03c5c85e901ca}, intrahash = {d5878964f65d884a81264059d7f2b2a2}, keywords = {amine benzoquinone copper methylthiomethylbenzimidazole methylthiomethylbenzimidazole;copper model oxidase prepn quinone tautomerism;review valence}, publisher = {{Wiley-VCH Verlag GmbH}}, timestamp = {2022-06-15T09:26:56.000+0200}, title = {Synthetic and spectroscopic approaches to the copper/quinone-coupled center in amine oxidases: Bioinorg. Chem}, year = 1997 }