%0 Journal Article %1 suherman_electrochemical_2019 %A Suherman, Alex L. %A Rasche, Bertold %A Godlewska, Beata %A Nicholas, Philip %A Herlihy, Shaun %A Caiger, Nigel %A Cowen, Philip J. %A Compton, Richard G. %D 2019 %J ACS Sens. %K imported %N 9 %P 2497--2506 %R 10.1021/acssensors.9b01176 %T Electrochemical Detection and Quantification of Lithium Ions in Authentic Human Saliva Using LiMn$_2$O$_4$-Modified Electrodes %U https://doi.org/10.1021/acssensors.9b01176 %V 4 %X We report an electrochemical sensor for the detection of lithium ions (Li+) in authentic human saliva at lithium manganese oxide (LiMn2O4)-modified glassy carbon electrodes (LMO-GCEs) and screen-printed electrodes (LMO-SPEs). The sensing strategy is based on an initial galvanostatic delithiation of LMO followed by linear stripping voltammetry (LSV) to detect the reinsertion of Li+ in the analyte. The process was investigated using powder X-ray diffraction and voltammetry. LSV measurements reveal a measurable lower limit of 50.0 μM in both LiClO4 aqueous solutions and synthetic saliva samples, demonstrating the applicability of the proposed analytical method down to low Li+ concentrations. Four different samples of authentic human saliva were then analyzed with the established sensing strategy using LMO-SPEs, showing good linearity over a concentration range up to 5.0 mM Li+ with high reproducibility (RSD \textless 7\%) and applicability for routine monitoring purposes. The total time needed to analyze a sample is less than 3 min.

@article{suherman_electrochemical_2019, abstract = {We report an electrochemical sensor for the detection of lithium ions (Li+) in authentic human saliva at lithium manganese oxide (LiMn2O4)-modified glassy carbon electrodes (LMO-GCEs) and screen-printed electrodes (LMO-SPEs). The sensing strategy is based on an initial galvanostatic delithiation of LMO followed by linear stripping voltammetry (LSV) to detect the reinsertion of Li+ in the analyte. The process was investigated using powder X-ray diffraction and voltammetry. LSV measurements reveal a measurable lower limit of 50.0 μM in both LiClO4 aqueous solutions and synthetic saliva samples, demonstrating the applicability of the proposed analytical method down to low Li+ concentrations. Four different samples of authentic human saliva were then analyzed with the established sensing strategy using LMO-SPEs, showing good linearity over a concentration range up to 5.0 mM Li+ with high reproducibility (RSD {\textless} 7\%) and applicability for routine monitoring purposes. The total time needed to analyze a sample is less than 3 min.}, added-at = {2024-03-25T12:35:57.000+0100}, author = {Suherman, Alex L. and Rasche, Bertold and Godlewska, Beata and Nicholas, Philip and Herlihy, Shaun and Caiger, Nigel and Cowen, Philip J. and Compton, Richard G.}, biburl = {https://puma.ub.uni-stuttgart.de/bibtex/2b11d2135908a5d60a8a29fb80396a8be/brasche}, doi = {10.1021/acssensors.9b01176}, file = {ACS Full Text Snapshot:files/4097/acssensors.html:text/html;Suherman et al_2019_Electrochemical Detection and Quantification of Lithium Ions in Authentic Human.pdf:files/4096/Suherman et al_2019_Electrochemical Detection and Quantification of Lithium Ions in Authentic Human.pdf:application/pdf}, interhash = {5ea3b4bebecd47c0c4e4dd912afc109a}, intrahash = {b11d2135908a5d60a8a29fb80396a8be}, journal = {ACS Sens.}, keywords = {imported}, month = sep, number = 9, pages = {2497--2506}, timestamp = {2024-03-25T12:35:57.000+0100}, title = {Electrochemical {Detection} and {Quantification} of {Lithium} {Ions} in {Authentic} {Human} {Saliva} {Using} {LiMn}$_{\textrm{2}}${O}$_{\textrm{4}}$-{Modified} {Electrodes}}, url = {https://doi.org/10.1021/acssensors.9b01176}, urldate = {2019-10-23}, volume = 4, year = 2019 }