The interaction between the metal and the potentially o- or p-quinonoid topaquinone (TPQ) ligand in the active site of Cu-dependent amine oxidases was approached using (Qn-)Cun+(L), Q = 3,5-di-tert-butyl-o-benzoquinone and L = 1-alkyl-2-(methylthiomethyl)-1H-benzimidazole, as a first model system for the enzymically relevant and EPR-detectable valence tautomerism (n = 1 or 2). The data are preceded by a review of model systems related to the function and coupling of Cu metal and the org. cofactor in copper-dependent amine oxidases, including the use of 2,4,5-trihydroxytoluene as a model for TPQ. on SciFinder(R)
%0 Conference Proceedings
%1 Rall.1997
%D 1997
%E Rall, Jochen
%E Waldhor, Eberhard
%E Schwederski, Brigitte
%E Schwach, Manuela
%E Kohlmann, Stephan
%E Kaim, Wolfgang.
%I Wiley-VCH Verlag GmbH
%K amine benzoquinone copper methylthiomethylbenzimidazole methylthiomethylbenzimidazole;copper model oxidase prepn quinone tautomerism;review valence
%T Synthetic and spectroscopic approaches to the copper/quinone-coupled center in amine oxidases: Bioinorg. Chem
%X The interaction between the metal and the potentially o- or p-quinonoid topaquinone (TPQ) ligand in the active site of Cu-dependent amine oxidases was approached using (Qn-)Cun+(L), Q = 3,5-di-tert-butyl-o-benzoquinone and L = 1-alkyl-2-(methylthiomethyl)-1H-benzimidazole, as a first model system for the enzymically relevant and EPR-detectable valence tautomerism (n = 1 or 2). The data are preceded by a review of model systems related to the function and coupling of Cu metal and the org. cofactor in copper-dependent amine oxidases, including the use of 2,4,5-trihydroxytoluene as a model for TPQ. on SciFinder(R)
@proceedings{Rall.1997,
abstract = {The interaction between the metal and the potentially o- or p-quinonoid topaquinone (TPQ) ligand in the active site of Cu-dependent amine oxidases was approached using (Qn-)Cun+(L), Q = 3,5-di-tert-butyl-o-benzoquinone and L = 1-alkyl-2-(methylthiomethyl)-1H-benzimidazole, as a first model system for the enzymically relevant and EPR-detectable valence tautomerism (n = 1 or 2). The data are preceded by a review of model systems related to the function and coupling of Cu metal and the org. cofactor in copper-dependent amine oxidases, including the use of 2,4,5-trihydroxytoluene as a model for TPQ. [on SciFinder(R)]},
added-at = {2019-07-15T13:41:23.000+0200},
biburl = {https://puma.ub.uni-stuttgart.de/bibtex/2d5878964f65d884a81264059d7f2b2a2/b_schwederski},
editor = {Rall, Jochen and Waldhor, Eberhard and Schwederski, Brigitte and Schwach, Manuela and Kohlmann, Stephan and Kaim, Wolfgang.},
interhash = {6de770c5601250d356e03c5c85e901ca},
intrahash = {d5878964f65d884a81264059d7f2b2a2},
keywords = {amine benzoquinone copper methylthiomethylbenzimidazole methylthiomethylbenzimidazole;copper model oxidase prepn quinone tautomerism;review valence},
publisher = {{Wiley-VCH Verlag GmbH}},
timestamp = {2019-07-15T11:42:10.000+0200},
title = {Synthetic and spectroscopic approaches to the copper/quinone-coupled center in amine oxidases: Bioinorg. Chem},
year = 1997
}