Article,

Temperature-insensitive microemulsions formulated from octyl monoglucoside and alcohols: potential candidates for applications.

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Tenside Surfactants Detergents, (2001)

Abstract

Microemulsion formulations based on non-toxic alkyl glucosides (CmGn) are of interest for applications in pharmaceutical and cosmetic products. In this work we demonstrate the favorable properties of quaternary microemulsions consisting of water - oil - C8G1 - alcohol. As alcohols we used n-octanol as well as the non-toxic geraniol (C10H17OH). Microemulsions with geraniol are potential candidates for pharmaceutical applications. We show for the first time by simultaneous phase behavior, SANS and interfacial tension measurements a quantitative correlation between the curvature and the composition of the interfacial film. We can relate the behavior of quaternary, temperature-insensitive microemulsions based on alkyl glucosides to that of ternary nonionic systems which exhibit a temperature-dependent curvature of the film. Thus, we are able to compare directly the effect of the temperature and the concentration of alcohol in the interfacial film. Both are important tuning parameters for the curvature, helping to formulate microemulsions with the desired properties in practical applications

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