IL15-Based Trifunctional Antibody-Fusion Proteins with Costimulatory TNF-Superfamily Ligands in the Single-Chain Format for Cancer Immunotherapy. Molecular Cancer Therapeutics, (18)7:1278-1288, AACR, 2019. [PUMA: ubs_10004 ubs_20006 ubs_30063 ubs_40093 unibibliografie wos]
Exploratory multiplex tissue image analysis of the impact of heterogeneity in the microenvironment of primary colorectal cancer on apoptosis markers in patients. Proceedings: AACR Annual Meeting 2019, 79, 13, Suppl.:LB-088, AACR, Philadelphia, Pa., 2019. [PUMA: ubs_10004 ubs_20006 ubs_30063 ubs_40096 unibibliografie wos]
Back-to-Germline (B2G) Procedure for Antibody Devolution. Antibodies, (8)3:45, MDPI, 2019. [PUMA: oa ubs_10004 ubs_20006 ubs_30063 ubs_40093 unibibliografie wos]
Exogenous activation of tumor necrosis factor receptor 2 promotes recovery from sensory and motor disease in a model of multiple sclerosis. Brain, Behavior and Immunity, (81):247-259, Elsevier, 2019. [PUMA: mult ubs_10004 ubs_10021 ubs_20006 ubs_20018 ubs_30063 ubs_30162 ubs_40093 unibibliografie wos]
RALB GTPase : A critical regulator of DR5 cell surface expression and TRAIL sensitivity in RAS mutant colorectal cancer. Proceedings: AACR Annual Meeting 2019, 79, 13, Suppl.:5103, AACR, Philadelphia, Pa., 2019. [PUMA: ubs_10004 ubs_20006 ubs_30063 ubs_40096 unibibliografie wos]
EGFR-Targeted TRAIL and a Smac Mimetic Synergize to Overcome Apoptosis Resistance in KRAS Mutant Colorectal Cancer Cells. PLOS ONE, (9)9:e107165, PLOS, 2014. [PUMA: f2014 oa oafonds ubs_10004 ubs_20006 ubs_30063 ubs_40093 ubs_40095 uni unibibliografie]
Selective Targeting of TNF Receptors as a Novel Therapeutic Approach. Frontiers in Cell and Developmental Biology, (8):401, Frontiers, 2020. [PUMA: dfg f2020 mult oa oafonds ubs_10004 ubs_20006 ubs_30063 ubs_40093 unibibliografie]
Reconstructing Temporal and Spatial Dynamics from Single-Cell Pseudotime Using Prior Knowledge of Real Scale Cell Densities. Scientific Reports, (10):3619, Springer Nature, 2020. [PUMA: dfg f2020 mult oa oafonds ubs_10004 ubs_10007 ubs_20006 ubs_20011 ubs_30063 ubs_30113 ubs_40096 ubs_40173 ubs_40364 unibibliografie]
Spatiotemporal Control of Intracellular Membrane Trafficking by Rho GTPases. Cells, (8)12:1478, MDPI, 2019. [PUMA: dfg f2019 mult oa oafonds ubs_10004 ubs_20006 ubs_30063 ubs_40095 ubs_40096 unibibliografie]
Superior Treg-Expanding Properties of a Novel Dual-Acting Cytokine Fusion Protein. Frontiers in Pharmacology, (10):1490, Frontiers Media, 2019. [PUMA: dfg f2019 mult oa oafonds ubs_10004 ubs_20006 ubs_30063 ubs_40093 ubs_40096 unibibliografie]
Continuous Infusion of an Agonist of the Tumor Necrosis Factor Receptor 2 in the Spinal Cord Improves Recovery After Traumatic Contusive Injury. CNS Neuroscience & Therapeutics, (25)8:884-893, Wiley, 2019. [PUMA: mult oa ubs_10004 ubs_20006 ubs_30063 ubs_40093 unibibliografie wos]
The Short-Chain Dehydrogenase/Reductase Engineering Database (SDRED): a Classification and Analysis System for a Highly Diverse Enzyme Family. Proteins : Structure, Function, and Bioinformatics, (87)6:443-451, Wiley, 2019. [PUMA: mult ubs_10003 ubs_10004 ubs_20003 ubs_20006 ubs_30063 ubs_30187 ubs_40093 ubs_40353 unibibliografie wos]
Lipid-dependent coupling of secretory cargo sorting and trafficking at the trans-Golgi network. FEBS Letters, (593)17:2412-2427, Wiley, 2019. [PUMA: oa ubs_10004 ubs_20006 ubs_30063 ubs_40096 unibibliografie wos]
Diabody-Ig: a novel platform for the generation of multivalent and multispecific antibody molecules. mAbs, (11)5:919-929, Landes Bioscience, 2019. [PUMA: ubs_10004 ubs_20006 ubs_30063 ubs_40093 unibibliografie wos]
Patient-derived colonic organoids as a model to study pharmacogenetics. Naunyn-Schmiedeberg's Archives of Pharmacology, 392, 1:S54, Springer, Berlin, 2019. [PUMA: ubs_10004 ubs_20006 ubs_30063 ubs_40093 ubs_40095 unibibliografie wos]
hmmr mediates anterior neural tube closure and morphogenesis in the frog Xenopus. Developmental biology, (430)1:188-201, Elsevier, 2017. [PUMA: ubs_10004 ubs_20006 ubs_30063 ubs_40096 unibibliografie wos]
Potential of activatable FAP-targeting immunoliposomes in intraoperative imaging of spontaneous metastases. Biomaterials, (88):70-82, Elsevier, 2016. [PUMA: ubs_10004 ubs_20006 ubs_30063 ubs_40093 unibibliografie wos]
Secretory pathway optimization of CHO producer cells by co-engineering of the mitosRNA-1978 target genes CerS2 and Tbc1D20. Metabolic engineering, (40):69-79, Elsevier, 2017. [PUMA: oa ubs_10004 ubs_20006 ubs_30063 unibibliografie wos]
On the relationship between cell cycle analysis with ergodic principles and age-structured cell population models. Journal of theoretical biology, (414):91-102, Elsevier, 2017. [PUMA: mult ubs_10004 ubs_10007 ubs_20006 ubs_20011 ubs_30063 ubs_30113 ubs_40094 ubs_40173 unibibliografie wos]
An EGF receptor targeting Ranpirnase-diabody fusion protein mediates potent antitumour activity in vitro and in vivo. Cancer letters, (357)1:364-373, Elsevier, 2015. [PUMA: ubs_10004 ubs_20006 ubs_30063 unibibliografie wos]
Bispecific antibodies. Drug discovery today, (20)7:838-847, Elsevier, 2015. [PUMA: ubs_10004 ubs_20006 ubs_30063 unibibliografie wos]
Bispecific single-chain diabody-immunoliposomes targeting endoglin (CD105) and fibroblast activation protein (FAP) simultaneously. Journal of controlled release, (201):56-67, Elsevier, 2015. [PUMA: ubs_10004 ubs_20006 ubs_30063 unibibliografie wos]
Tailoring the stealth properties of biocompatible polysaccharide nanocontainers. Biomaterials, (49):125-134, Elsevier, 2015. [PUMA: ubs_10004 ubs_20006 ubs_30063 unibibliografie wos]
Activatable bispecific liposomes bearing fibroblast activation protein directed single chain fragment/Trastuzumab deliver encapsulated cargo into the nuclei of tumor cells and the tumor microenvironment simultaneously. Acta biomaterialia, (54):281-293, Elsevier, 2017. [PUMA: oa ubs_10004 ubs_20006 ubs_30063 ubs_40093 unibibliografie wos]
Rho regulation: DLC proteins in space and time. Cellular signalling, (27)8:1643-1651, Elsevier, 2015. [PUMA: ubs_10004 ubs_20006 ubs_30063 unibibliografie wos]
Chemotactic synthetic vesicles: Design and applications in blood-brain barrier crossing. Science advances, (3)8:e1700362, AAAS, 2017. [PUMA: oa ubs_10004 ubs_20006 ubs_30063 ubs_40096 unibibliografie wos]
The making of bispecific antibodies. mAbs, (9)2:182-212, Taylor & Francis, 2017. [PUMA: oa ubs_10004 ubs_20006 ubs_30063 ubs_40093 unibibliografie wos]
Superior Properties of Fc-comprising scTRAIL Fusion Proteins. Molecular cancer therapeutics, (16)12:2792-2802, American Association for Cancer Research, 2017. [PUMA: mult ubs_10004 ubs_20006 ubs_30063 ubs_40093 ubs_40096 unibibliografie wos]
Protein kinase D exerts neuroprotective functions during oxidative stress via nuclear factor kappa B-independent signaling pathways. Journal of neurochemistry, (142)6:948-961, Wiley, 2017. [PUMA: ubs_10004 ubs_20006 ubs_30063 ubs_40096 unibibliografie wos]
Tumor-targeted costimulation with antibody-fusion proteins improves bispecific antibody-mediated immune response in presence of immunosuppressive factors. Oncoimmunology, (6)12:e1361594, Taylor & Francis, 2017. [PUMA: ubs_10004 ubs_20006 ubs_30063 ubs_40093 unibibliografie wos]
A fast and effective determination of the biodistribution and subcellular localization of fluorescent immunoliposomes in freshly excised animal organs. BMC biotechnology, (17):8, BioMed Central, 2017. [PUMA: oa ubs_10004 ubs_20006 ubs_30063 ubs_40093 unibibliografie wos]
Inhibition of HER3 activation and tumor growth with a human antibody binding to a conserved epitope formed by domain III and IV. mAbs, (9)5:831-843, Taylor & Francis, 2017. [PUMA: mult ubs_10004 ubs_20006 ubs_30063 ubs_40093 ubs_40095 unibibliografie wos]
Selective activation of tumor necrosis factor receptor 2 induces anti-inflammatory responses and alleviates experimental arthritis. Abstracts of DGfI 2017 / 47th Annual Meeting of the German Society for Immunology, 47, Suppl. 2:131, Wiley, Weinheim, 2017. [PUMA: ubs_10004 ubs_20006 ubs_30063 ubs_40093 unibibliografie wos]
Sphingolipid metabolic flow controls phosphoinositide turnover at the trans-Golgi network. The EMBO journal, (36)12:1736-1754, Wiley, 2017. [PUMA: ubs_10004 ubs_20006 ubs_30063 ubs_40096 unibibliografie wos]
Bcl-2-Ome - a database and interactive web service for dissecting the Bcl-2 interactome. Cell death and differentiation, (24)1:192, Nature Publishing Group, 2017. [PUMA: oa ubs_10004 ubs_20006 ubs_30063 unibibliografie wos]
Ras and Rab interactor 1 controls neuronal plasticity by coordinating dendritic filopodial motility and AMPA receptor turnover. Molecular biology of the cell, (28)2:285-295, American Society for Cell Biology, 2017. [PUMA: oa ubs_10004 ubs_20006 ubs_30063 ubs_40096 unibibliografie wos]
A Stepwise Integrated Approach to Personalized Risk Predictions in Stage III Colorectal Cancer. Clinical cancer research, (23)5:1200-1212, American Association for Cancer Research, 2017. [PUMA: ubs_10004 ubs_20006 ubs_30063 unibibliografie wos]
The Ability of Nitric Oxide to Lower Intraocular Pressure Is Dependent on Guanylyl Cyclase. Investigative ophthalmology & visual science, (58)11:4826-4835, Association for Research in Vision and Ophthalmology, 2017. [PUMA: ubs_10004 ubs_20006 ubs_30063 ubs_40095 unibibliografie wos]
Examining the In Vitro Efficacy of the IAP Antagonist Birinapant as a Single Agent or in Combination With Dacarbazine to Induce Melanoma Cell Death. Oncology research, (25)9:1489-1494, Cognizant Communication, 2017. [PUMA: ubs_10004 ubs_20006 ubs_30063 ubs_40096 unibibliografie wos]
Advancing targeted co-stimulation with antibody-fusion proteins by introducing TNF superfamily members in a single-chain format. OncoImmunology, (5)11:e1238540, Taylor & Francis, 2016. [PUMA: ubs_10004 ubs_20006 ubs_30063 ubs_40093 unibibliografie wos]
Oncogenic Ras triggers hyperproliferation and impairs polarized colonic morphogenesis by autocrine ErbB3 signaling. Oncotarget, (7)33:53526-53539, Impact Journals LLC, 2016. [PUMA: mult ubs_10004 ubs_20006 ubs_30063 ubs_40093 ubs_40095 unibibliografie wos]
An optimized antibody-single-chain TRAIL fusion protein for cancer therapy. mAbs, (8)5:879-891, Taylor & Francis, 2016. [PUMA: mult ubs_10004 ubs_20006 ubs_30063 ubs_40093 ubs_40096 unibibliografie wos]
The polarity protein Scribble positions DLC3 at adherens junctions to regulate Rho signaling. Journal of cell science, (129)19:3583-3596, Company of Biologists, 2016. [PUMA: mult ubs_10004 ubs_20006 ubs_30063 ubs_40095 ubs_40096 unibibliografie wos]
Pharmacokinetic properties of IgG and various Fc fusion proteins in mice. mAbs, (8)1:120-128, Taylor & Francis, 2016. [PUMA: mult ubs_10004 ubs_20006 ubs_30063 ubs_40093 ubs_40096 unibibliografie wos]
Predicting the cell death responsiveness and sensitization of glioma cells to TRAIL and temozolomide. Oncotarget, (7)38:61295-61311, Impact Journals LLC, 2016. [PUMA: ubs_10004 ubs_20006 ubs_30063 ubs_40096 unibibliografie wos]
Loss of p53 expression is accompanied by upregulation of beta-catenin in meningiomas: a concomitant reciprocal expression. International journal of experimental pathology, (97)2:159-169, Wiley, 2016. [PUMA: ubs_10004 ubs_20006 ubs_30063 ubs_40096 unibibliografie wos]
Half-life extended biotherapeutics. Expert opinion on biological therapy, (16)7:903-915, Taylor & Francis, 2016. [PUMA: ubs_10004 ubs_20006 ubs_30063 ubs_40093 unibibliografie wos]
Essential protective role of tumor necrosis factor receptor 2 in neurodegeneration. Proceedings of the National Academy of Sciences of the United States of America, (113)43:12304-12309, National Academy of Sciences, 2016. [PUMA: ubs_10004 ubs_20006 ubs_30063 ubs_40093 unibibliografie wos]
Immunoliposomes for Targeted Delivery of an Antifibrotic Drug. Molecular pharmaceutics, (12)9:3146-3157, ACS, 2015. [PUMA: ubs_10004 ubs_20006 ubs_30063 unibibliografie wos]
Interrelation of Oxidative Stress and Inflammation in Neurodegenerative Disease: Role of TNF. Oxidative medicine and cellular longevity, (2015):610813, Hindawi, 2015. [PUMA: ubs_10004 ubs_20006 ubs_30063 unibibliografie wos]