Publications

Philipp Schnee, Michel Choudalakis, Sara Weirich, Mina S. Khella, Henrique Carvalho, Jürgen Pleiss, and Albert Jeltsch. Mechanistic basis of the increased methylation activity of the SETD2 protein lysine methyltransferase towards a designed super-substrate peptide. Communications Chemistry, (5)1:139--, 2022. [PUMA: EXC2075 PN2 PN2-5 curated] URL

Mina S. Khella, Philipp Schnee, Sara Weirich, Tan Bui, Alexander Bröhm, Pavel Bashtrykov, Jürgen Pleiss, and Albert Jeltsch. The T1150A cancer mutant of the protein lysine dimethyltransferase NSD2 can introduce H3K36 trimethylation. Journal of Biological Chemistry, (299)6:104796--, 2023. [PUMA: EXC2075 PN2 PN2-5 curated] URL

Philipp Schnee, Jürgen Pleiss, and Albert Jeltsch. Approaching the catalytic mechanism of protein lysine methyltransferases by biochemical and simulation techniques. Critical Reviews in Biochemistry and Molecular Biology, (59)1-2:20-68, Taylor & Francis, 2024. [PUMA: EXC2075 PN2 PN2-5 curated] URL

Sara Weirich, Denis Kusevic, Philipp Schnee, Jessica Reiter, Jürgen Pleiss, and Albert Jeltsch. Discovery of NSD2 non-histone substrates and design of a super-substrate. Communications Biology, (7)1:707--, 2024. [PUMA: EXC2075 PN2 PN2-5 curated] URL

Alexandra Mack, Max Emperle, Philipp Schnee, Sabrina Adam, Jürgen Pleiss, Pavel Bashtrykov, and Albert Jeltsch. Preferential Self-interaction of DNA Methyltransferase DNMT3A Subunits Containing the R882H Cancer Mutation Leads to Dominant Changes of Flanking Sequence Preferences. Journal of Molecular Biology, (434)7:167482, Elsevier BV, 2022. [PUMA: EXC2075 PN2 PN2-5 PN2-6 PN2-6(II) curated] URL