Publications

Kayla L Nguyen, Ishaan J Bhatt, Shruti Gupta, Nazaf Showkat, Kathryn A Swanson, Roman Fischer, Roland E Kontermann, Klaus Pfizenmaier, Valerie Bracchi-Ricard, and John R Bethea. Tumor necrosis factor receptor 2 activation elicits sex-specific effects on cortical myelin proteins and functional recovery in a model of multiple sclerosis. Brain research bulletin, (207):110885--110885, United States, January 2024. [PUMA: 2024 izi kontermann pfizenmaier] URL

Leila Abassi, Federico Bertoglio, Željka Mačak Šafranko, Thomas Schirrmann, Marina Greweling-Pils, Oliver Seifert, Fawad Khan, Maeva Katzmarzyk, Henning Jacobsen, Natascha Gödecke, Philip Alexander Heine, André Frenzel, Helena Nowack, Stefan Dübel, Ivan-Christian Kurolt, Roland E Kontermann, Alemka Markotić, Maren Schubert, Michael Hust, and Luka Čičin-Šain. Evaluation of the Neutralizing Antibody STE90-C11 against SARS-CoV-2 Delta Infection and Its Recognition of Other Variants of Concerns. Viruses, (15)11:2153--, Switzerland, October 2023. [PUMA: 2023 izi kontermann] URL

Natalia Ortí-Casañ, Ate S Boerema, Karina Köpke, Amber Ebskamp, Jan Keijser, Yuequ Zhang, Tingting Chen, Amalia M Dolga, Kerensa Broersen, Roman Fischer, Klaus Pfizenmaier, Roland E Kontermann, and Ulrich L M Eisel. The TNFR1 antagonist Atrosimab reduces neuronal loss, glial activation and memory deficits in an acute mouse model of neurodegeneration. Scientific reports, (13)1:10622--10622, England, June 2023. [PUMA: 2023 izi kontermann pfizenmaier] URL

Nora Hornig, Vanessa Kermer, Katharina Frey, Philipp Diebolder, Roland E. Kontermann, and Dafne Müller. Combination of a bispecific antibody and costimulatory antibody-ligand fusion proteins for targeted cancer immunotherapy. Journal of Immunotherapy, (35)5:418--429, June 2012. [PUMA: 2012 izi kontermann] URL

Roland E Kontermann. Alternative antibody formats.. Current opinion in molecular therapeutics, (12)2:176--183, 2010. [PUMA: 2010 izi kontermann] URL

Fabian Richter, Oliver Seifert, Andreas Herrmann, Klaus Pfizenmaier, and Roland E. Kontermann. Improved monovalent TNF receptor 1-selective inhibitor with novel heterodimerizing Fc. mAbs, 1--13, Taylor & Francis, March 2019. [PUMA: 2019 izi kontermann pfizenmaier] URL

A Rau, W S Lieb, O Seifert, J Honer, D Birnstock, F Richter, N Aschmoneit, M A Olayioye, and R E Kontermann. Inhibition of tumor cell growth and cancer stem cell expansion by a bispecific antibody targeting EGFR and HER3. Mol Cancer Ther, May 2020. [PUMA: 2020 izi kontermann olayioye] URL

Roland E Kontermann, Peter Scheurich, and Klaus Pfizenmaier. Antagonists of TNF action: clinical experience and new developments. Expert Opinion on Drug Discovery, (4)3:279--292, 2009. [PUMA: 2009 izi kontermann pfizenmaier] URL

Liane Schuster, Oliver Seifert, Stefanie Vollmer, Roland E. Kontermann, Burkhard Schlosshauer, and Hanna Hartmann. Immunoliposomes for Targeted Delivery of an Antifibrotic Drug. Molecular Pharmaceutics, (12)9:3146--3157, September 2015. [PUMA: 2015 izi kontermann] URL

Roman Fischer, Harald Wajant, Roland Kontermann, Klaus Pfizenmaier, and Olaf Maier. Astrocyte-specific activation of TNFR2 promotes oligodendrocyte maturation by secretion of leukemia inhibitory factor. Glia, (62)2:272--283, February 2014. [PUMA: 2014 izi kontermann pfizenmaier] URL

Ronny Rüger, Felista L. Tansi, Markus Rabenhold, Frank Steiniger, Roland E. Kontermann, Alfred Fahr, and Ingrid Hilger. In vivo near-infrared fluorescence imaging of FAP-expressing tumors with activatable FAP-targeted, single-chain Fv-immunoliposomes. Journal of Controlled Release, (186):1--10, July 2014. [PUMA: 2014 izi kontermann] URL

A. Hesse, D. Kosmides, R. E. Kontermann, and D. M. Nettelbeck. Tropism Modification of Adenovirus Vectors by Peptide Ligand Insertion into Various Positions of the Adenovirus Serotype 41 Short-Fiber Knob Domain. Journal of Virology, (81)6:2688--2699, 2007. [PUMA: 2007 izi kontermann] URL

Felix Unverdorben, Fabian Richter, Meike Hutt, Oliver Seifert, Pauline Malinge, Nicolas Fischer, and Roland E. Kontermann. Pharmacokinetic properties of IgG and various Fc fusion proteins in mice. mAbs, (8)1:120--128, January 2016. [PUMA: 2016 izi kontermann] URL

Tanja Padutsch, Sendetski Maksim, Carina Huber, Nathalie Peters, Klaus Pfizenmaier, John R Bethea, Roland E. Kontermann, and Roman Fischer. Superior Treg-expanding properties of a novel dual-acting cytokine fusion protein. Frontiers in Pharmacology, (10):1490, Frontiers, 2019. [PUMA: 2019 fischer izi kontermann] URL

Pilar Puerto-Camacho, Ana Teresa Amaral, Salah-Eddine Lamhamedi-Cherradi, Brian A Menegaz, Helena Castillo-Ecija, José Luis Ordóñez, Saioa Dominguez-Hormaetxe, Carmen Jordan-Perez, Juan Diaz-Martin, Laura Romero-Pérez, Maria Lopez-Alvarez, Gema Civantos-Jubera, María José Robles-Frias, Michele Biscuola, Cristina Ferrer, Jaume Mora, Branko Cuglievan, Keri L. Schadler, Oliver Seifert, Roland E. Kontermann, Klaus Pfizenmaier, Laureano Simon, Myriam Fabre, Angel M. Carcaboso, Joseph A Ludwig, and Enrique de Álava. Preclinical efficacy of endoglin-targeting antibody-drug conjugates for the treatment of Ewing sarcoma. Clinical Cancer Research, clincanres.0936.2018, November 2018. [PUMA: 2018 izi kontermann] URL

Robert Lindner, Anna Moosmann, Alexander Dietrich, Heiner Böttinger, Roland Kontermann, and Martin Siemann-Herzberg. Process development of periplasmatically produced single chain fragment variable against epidermal growth factor receptor in Escherichia coli. Journal of Biotechnology, (192):136--145, Elsevier BV, December 2014. [PUMA: 2014 izi kontermann] URL

Verena Berger, Fabian Richter, Kirstin Zettlitz, Felix Unverdorben, Peter Scheurich, Andreas Herrmann, Klaus Pfizenmaier, and Roland E. Kontermann. An anti-TNFR1 scFv-HSA fusion protein as selective antagonist of TNF action. Protein Engineering, Design and Selection, (26)10:581--587, October 2013. [PUMA: 2013 izi kontermann pfizenmaier] URL

Philipp Diebolder, Armin Keller, Stephanie Haase, Anne Schlegelmilch, Jonathan D Kiefer, Tamana Karimi, Tobias Weber, Gerhard Moldenhauer, Roland Kehm, Anna M Eis-Hübinger, Dirk Jäger, Philippe A Federspil, Christel Herold-Mende, Gerhard Dyckhoff, Roland E Kontermann, Michaela AE Arndt, and Jürgen Krauss. Generation of “LYmph Node Derived Antibody Libraries” (LYNDAL) for selecting fully human antibody fragments with therapeutic potential. mAbs, (6)1:130-142, Taylor & Francis, 2014. [PUMA: 2014 izi kontermann] URL

Martin Siegemund, Oliver Seifert, Maria Zarani, Tamara Dzinić, Valentino De Leo, Doris Göttsch, Sabine Münkel, Meike Hutt, Klaus Pfizenmaier, and Roland E. Kontermann. An optimized antibody-single-chain TRAIL fusion protein for cancer therapy. mAbs, (8)5:879--891, July 2016. [PUMA: 2016 izi kontermann pfizenmaier] URL

Kirstin A. Zettlitz, Julia Seitter, Dafne Müller, and Roland E. Kontermann. Humanization of a mouse monoclonal antibody directed against a cell surface-exposed epitope of membrane-associated heat shock protein 70 (Hsp70). Molecular Biotechnology, (46)3:265--278, 2010. [PUMA: 2010 izi kontermann] URL