Publications

Jonathan Blum, Markus Brüll, Jan G. Hengstler, Daniel R. Dietrich, Andreas J. Gruber, Michele Dipalo, Udo Kraushaar, Iris Mangas, Andrea Terron, Ellen Fritsche, Philip Marx-Stoelting, Barry Hardy, Andreas Schepky, Sylvia Escher, Thomas Hartung, Robert Landsiedel, Alex Odermatt, Magdalini Sachana, Katharina Koch, Arif Dönmez, Stefan Masjosthusmann, Kathrin Bothe, Stefan Schildknecht, Mario Beilmann, Joost B. Beltman, Suzanne Fitzpatrick, Aswin Mangerich, Markus Rehm, Silvia Tangianu, Franziska M. Zickgraf, Hennicke Kamp, Gerhard Burger, Bob van de Water, Nicole Kleinstreuer, Andrew White, and Marcel Leist. The long way from raw data to NAM-based information: Overview on data layers and processing steps. ALTEX - Alternatives to animal experimentation, (42)1:167-180--, January 2025. [PUMA: 2025 izi morrison] URL

Yun Qiu, Juliana A. Hüther, Bianca Wank, Antonia Rath, René Tykwe, Maceler Aldrovandi, Bernhard Henkelmann, Julia Mergner, Toshitaka Nakamura, Sabine Laschat, Marcus Conrad, Daniela Stöhr, and Markus Rehm. Interplay of ferroptotic and apoptotic cell death and its modulation by BH3-mimetics. Cell Death & Differentiation, Apr 29, 2025. [PUMA: 2025 izi morrison] URL

Kristin Entrop, Senait Wieske, and Markus Rehm. Why Bax detection in >1400 publications might be flawed. Cell Death & Disease, (15)12:880, Dec 5, 2024. [PUMA: 2024 izi morrison] URL

Tobias B Beigl, Alexander Paul, Thomas P Fellmeth, Dang Nguyen, Lynn Barber, Sandra Weller, Benjamin Schäfer, Bernhard F Gillissen, Walter E Aulitzky, Hans-Georg Kopp, Markus Rehm, David W Andrews, Kristyna Pluhackova, and Frank Essmann. BCL-2 and BOK regulate apoptosis by interaction of their C-terminal transmembrane domains. EMBO reports, (25)9:3896-3924--3924, John Wiley & Sons, Ltd, September 2024. [PUMA: 2024 izi morrison simtech] URL

Chiara Boccellato, and Markus Rehm. TRAIL-induced apoptosis and proteasomal activity – Mechanisms, signalling and interplay. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 119688, 2024. [PUMA: 2024 izi morrison] URL

Daniela Stöhr, Albert Jeltsch, and Markus Rehm. TRAIL receptor signaling: From the basics of canonical signal transduction toward its entanglement with ER stress and the unfolded protein response.. Cell Death Regulation in Health and Disease-Part A, 57, Academic Press, 2020. [PUMA: exc2075 morrison]

Cristiano Guttà, Arman Rahman, Claudia Aura, Peter Dynoodt, Emilie M. Charles, Elodie Hirschenhahn, Jesuchristopher Joseph, Jasper Wouters, Ciaran de Chaumont, Mairin Rafferty, Madhuri Warren, Joost J. van den Oord, William M. Gallagher, and Markus Rehm. Low expression of pro-apoptotic proteins Bax, Bak and Smac indicates prolonged progression-free survival in chemotherapy-treated metastatic melanoma. Cell Death & Disease, (11)2:124, Nature Publishing Group, February 2020. [PUMA: 2020 EXC2075 izi morrison myown pn2 simtech] URL

Karsten Kuritz, Daniela Stöhr, Daniela Simone Maichl, Nadine Pollak, Markus Rehm, and Frank Allgöwer. Reconstructing temporal and spatial dynamics from single-cell pseudotime using prior knowledge of real scale cell densities. Scientific Reports, (10)1:3619, Nature Publishing Group, December 2020. [PUMA: 2020 EXC2075 izi morrison pn2 simtech] URL

Cathrin Hagenlocher, Robin Siebert, Bruno Taschke, Senait Wieske, Angelika Hausser, and Markus Rehm. ER stress-induced cell death proceeds independently of the TRAIL-R2 signaling axis in pancreatic β cells. Cell Death Discovery, (8)1:34, Jan 24, 2022. [PUMA: 2022 EXC2075 hausser izi morrison pn2 simtech] URL

Wolfgang Ehlers, Markus Morrison (Rehm), Patrick Schröder, Daniela Stöhr, and Arndt Wagner. Multiphasic modelling and computation of metastatic lung-cancer cell proliferation and atrophy in brain tissue based on experimental data. Biomechanics and Modeling in Mechanobiology, 2021. [PUMA: 2021 EXC2075 izi morrison pn2 simtech] URL

Dirke Imig, Nadine Pollak, Frank Allgöwer, and Markus Rehm. Sample-based modeling reveals bidirectional interplay between cell cycle progression and extrinsic apoptosis. PLOS Computational Biology, (16)6:1-17, Public Library of Science, June 2020. [PUMA: 2020 EXC2075 izi morrison pn2 simtech] URL

Gavin Fullstone, Cristiano Guttà, Amatus Beyer, and Markus Rehm. The FLAME-accelerated signalling tool (FaST) for facile parallelisation of flexible agent-based models of cell signalling. npj Systems Biology and Applications, (6)1:10--, 2020. [PUMA: 2020 EXC2075 izi morrison pn2 simtech] URL

Daniela Stöhr, and Markus Rehm. Linking hyperosmotic stress and apoptotic sensitivity. The FEBS Journal, febs.15520, Blackwell Publishing Ltd, August 2020. [PUMA: 2020 EXC2075 izi morrison pn2 simtech] URL

Cristiano Guttà, Christoph Morhard, and Markus Rehm. Applying a GAN-based classifier to improve transcriptome-based prognostication in breast cancer. PLOS Computational Biology, (19)4:1-20, Public Library of Science, April 2023. [PUMA: 2023 EXC2075 izi morrison myown pn2 simtech] URL

Cristiano Guttà, Christoph Morhard, and Markus Rehm. T-GAN-D: a GAN-based classifier for breast cancer prognostication. Zenodo, October 2022. [PUMA: 2022 EXC2075 izi morrison myown pn2 simtech] URL

Chiara Boccellato, and Markus Rehm. Glioblastoma, from disease understanding towards optimal cell-based in vitro models. Cellular Oncology, Jun 28, 2022. [PUMA: 2022 EXC2075 izi morrison pn2 simtech] URL

Vesna Vetma, Cristiano Guttà, Nathalie Peters, Christian Praetorius, Meike Hutt, Oliver Seifert, Friedegund Meier, Roland Kontermann, Dagmar Kulms, and Markus Rehm. Convergence of pathway analysis and pattern recognition predicts sensitization to latest generation TRAIL therapeutics by IAP antagonism. Cell Death & Differentiation 2020, 1--16, Nature Publishing Group, February 2020. [PUMA: 2020 EXC2075 izi morrison myown pn2 simtech] URL

Christopher McCann, Anna Matveeva, Katherine McAllister, Tamas Sessler, Michael Fichtner, Steven Carberry, Markus Rehm, Jochen H.M. Prehn, and Daniel B. Longley. Development of a protein signature to enable clinical positioning of IAP inhibitors in colorectal cancer. The FEBS Journal, febs.15801, John Wiley & Sons, Ltd, March 2021. [PUMA: 2021 izi morrison] URL

D Stöhr, A Jeltsch, and M Rehm. TRAIL receptor signaling: From the basics of canonical signal transduction toward its entanglement with ER stress and the unfolded protein response. Int Rev Cell Mol Biol, (351):57-99, 2020. [PUMA: 2020 izi morrison] URL

Josip Skoko, Jan Rožanc, Emilie M. Charles, Leonidas G. Alexopoulos, and Markus Rehm. Post-treatment de-phosphorylation of p53 correlates with dasatinib responsiveness in malignant melanoma. BMC Cell Biology, (19)1:28, December 2019. [PUMA: 2019 izi morrison] URL