Applying a GAN-based classifier to improve transcriptome-based prognostication in breast cancer. PLOS Computational Biology, (19)4:1-20, Public Library of Science, April 2023. [PUMA: 2023 EXC2075 izi morrison myown pn2 simtech] URL
T-GAN-D: a GAN-based classifier for breast cancer prognostication. Zenodo, October 2022. [PUMA: 2022 EXC2075 izi morrison myown pn2 simtech] URL
Applying GAN-based data augmentation to improve transcriptome-based prognostication in breast cancer. medRxiv, Cold Spring Harbor Laboratory Press, October 2022. [PUMA: 2022 EXC2075 izi morrison myown pn2 simtech] URL
Melanoma 2.0. Skin cancer as a paradigm for emerging diagnostic technologies, computational modelling and artificial intelligence. Briefings in Bioinformatics, October 2022. [PUMA: 2022 EXC2075 izi morrison pn2 simtech] URL
Glioblastoma, from disease understanding towards optimal cell-based in vitro models. Cellular Oncology, Jun 28, 2022. [PUMA: 2022 EXC2075 izi morrison pn2 simtech] URL
Mitochondrial genome variations, mitochondrial-nuclear compatibility, and their association with metabolic diseases. Obesity, John Wiley & Sons, Ltd, May 2022. [PUMA: 2022 EXC2075 izi morrison pn2 simtech] URL
ER stress-induced cell death proceeds independently of the TRAIL-R2 signaling axis in pancreatic β cells. Cell Death Discovery, (8)1:34, Jan 24, 2022. [PUMA: 2022 EXC2075 hausser izi morrison pn2 simtech] URL
Multiphasic modelling and computation of metastatic lung-cancer cell proliferation and atrophy in brain tissue based on experimental data. Biomechanics and Modeling in Mechanobiology, 2021. [PUMA: 2021 EXC2075 izi morrison pn2 simtech] URL
Low-Level Endothelial TRAIL-Receptor Expression Obstructs the CNS-Delivery of Angiopep-2 Functionalised TRAIL-Receptor Agonists for the Treatment of Glioblastoma. Molecules 2021, Vol. 26, Page 7582, (26)24:7582, Multidisciplinary Digital Publishing Institute, December 2021. [PUMA: 2021 EXC2075 izi morrison pn2 simtech] URL
Cell cycle progression and transmitotic apoptosis resistance promote escape from extrinsic apoptosis. Journal of cell science, jcs.258966--, England, November 2021. [PUMA: 2021 EXC2075 izi morrison pn2 simtech] URL
Proteasome inhibition triggers the formation of TRAIL receptor 2 platforms for caspase-8 activation that accumulate in the cytosol. Cell Death & Differentiation 2021, 1--9, Nature Publishing Group, August 2021. [PUMA: 2021 EXC2075 izi morrison pn2 simtech] URL
Marizomib sensitizes primary glioma cells to apoptosis induced by a latest-generation TRAIL receptor agonist. Cell Death & Disease, (12)7:647, Nature Publishing Group, July 2021. [PUMA: 2021 EXC2075 izi morrison pn2 simtech] URL
Linking hyperosmotic stress and apoptotic sensitivity. The FEBS Journal, febs.15520, Blackwell Publishing Ltd, August 2020. [PUMA: 2020 EXC2075 izi morrison pn2 simtech] URL
Sample-based modeling reveals bidirectional interplay between cell cycle progression and extrinsic apoptosis. PLOS Computational Biology, (16)6:1-17, Public Library of Science, June 2020. [PUMA: 2020 EXC2075 izi morrison pn2 simtech] URL
Stress-induced TRAILR2 expression overcomes TRAIL resistance in cancer cell spheroids. Cell Death & Differentiation, 2020. [PUMA: 2020 EXC2075 izi morrison pn2 simtech] URL
The apoptosome molecular timer synergises with XIAP to suppress apoptosis execution and contributes to prognosticating survival in colorectal cancer. Cell Death & Differentiation, 2020. [PUMA: 2020 EXC2075 izi morrison myown pn2 simtech] URL
The FLAME-accelerated signalling tool (FaST) for facile parallelisation of flexible agent-based models of cell signalling. npj Systems Biology and Applications, (6)1:10--, 2020. [PUMA: 2020 EXC2075 izi morrison pn2 simtech] URL
Reconstructing temporal and spatial dynamics from single-cell pseudotime using prior knowledge of real scale cell densities. Scientific Reports, (10)1:3619, Nature Publishing Group, December 2020. [PUMA: 2020 EXC2075 izi morrison pn2 simtech] URL
Convergence of pathway analysis and pattern recognition predicts sensitization to latest generation TRAIL therapeutics by IAP antagonism. Cell Death & Differentiation 2020, 1--16, Nature Publishing Group, February 2020. [PUMA: 2020 EXC2075 izi morrison myown pn2 simtech] URL
Low expression of pro-apoptotic proteins Bax, Bak and Smac indicates prolonged progression-free survival in chemotherapy-treated metastatic melanoma. Cell Death & Disease, (11)2:124, Nature Publishing Group, February 2020. [PUMA: 2020 EXC2075 izi morrison myown pn2 simtech] URL