L-valine production during growth of pyruvate dehydrogenase complex-deficient Corynebacterium glutamicum in the presence of ethanol or by inactivation of the transcriptional regulator SugR. Appl. Environ. Microbiol., (75)4:1197--1200, February 2009. [PUMA: Complex Corynebacterium Dehydrogenase Ethanol, Factors, Gene Knockout Pyruvate Techniques, Transcription Valine, glutamicum, myown]
Importance of NADPH supply for improved L-valine formation in Corynebacterium glutamicum. Biotechnol. Prog., (26)2:361--371, April 2010. [PUMA: Biological, Cell Corynebacterium Culture Fermentation, Glucose-6-Phosphate Isomerase, Media, Metabolic Metabolome Models, NADP, Networks Pathways, Techniques, Valine, and glutamicum, myown]
Application of metabolic engineering for the biotechnological production of L-valine. Appl. Microbiol. Biotechnol., (98)13:5859--5870, July 2014. [PUMA: Aerobiosis, Anaerobiosis, Biosynthetic Corynebacterium Engineering Escherichia Metabolic Pathways, Valine, coli, glutamicum, myown]
L-valine production with pyruvate dehydrogenase complex-deficient Corynebacterium glutamicum. Appl. Environ. Microbiol., (73)7:2079--2084, April 2007. [PUMA: Acid, Alanine Complex, Corynebacterium Dehydrogenase Fermentation, Isoleucine, Lysine, Pyruvate Pyruvic Valine, glutamicum, myown]
Application of a genetically encoded biosensor for live cell imaging of L-valine production in pyruvate dehydrogenase complex-deficient Corynebacterium glutamicum strains. PLoS ONE, (9)1:e85731, 2014. [PUMA: Biosensing Complex, Corynebacterium Dehydrogenase Fluorescence, Microfluidics Online Phenotype, Pyruvate Systems, Techniques, Valine, glutamicum, myown]
Acetohydroxyacid synthase, a novel target for improvement of L-lysine production by Corynebacterium glutamicum. Appl. Environ. Microbiol., (75)2:419--427, January 2009. [PUMA: Acetolactate Acid, Bacterial Butyrates Corynebacterium Deletion, Enzyme Expression Gene Inhibitors, Isoleucine, Kinetics, Leucine, Lysine, Profiling, Proteins, Pyruvic Sequence Synthase, Valine, glutamicum, myown]
Corynebacterium glutamicum tailored for high-yield L-valine production. Appl. Microbiol. Biotechnol., (79)3:471--479, June 2008. [PUMA: Bacterial Biomass, Biosynthetic Complex, Corynebacterium Dehydrogenase Engineering, Expression, Fermentation Gene Genetic Ketol-Acid Oxidoreductases, Pathways, Proteins, Pyruvate Reductoisomerase, Transaminases, Valine, glutamicum, myown]
The pyruvate dehydrogenase complex of Corynebacterium glutamicum: an attractive target for metabolic engineering. J. Biotechnol., (192 Pt B):339--345, December 2014. [PUMA: Acid, Amino Butanols, Complex, Corynebacterium Dehydrogenase Engineering, Isobutanol Metabolic Pyruvate Pyruvic Valine, acid and complex dehydrogenase engineering, glutamicum, myown organic production,]
Platform engineering of Corynebacterium glutamicum with reduced pyruvate dehydrogenase complex activity for improved production of L-lysine, L-valine, and 2-ketoisovalerate. Appl. Environ. Microbiol., (79)18:5566--5575, September 2013. [PUMA: Acids, Biomass, Complex, Corynebacterium Dehydrogenase Deletion, Down-Regulation, Engineering Expression, Gene Genetic, Glucose, Keto Lysine, Metabolic Networks Pathways, Promoter Pyruvate Recombination, Regions, Valine, and glutamicum, myown]
Impact of different CO2/HCO3- levels on metabolism and regulation in Corynebacterium glutamicum. J. Biotechnol., (168)4:331--340, December 2013. [PUMA: Alanine, Bacterial Bacterial, Biomass, CO(2)/HCO(3)(−), Carbon Corynebacterium DNA-Binding Dehydrogenase, Dioxide, Diphtheria Dissolved DtxR, Expression Gene Glucose, Glucosephosphate Proteins, Regulation, Thiamin Thiamine, Toxin, Valine, biosynthesis carbon dioxide, glutamicum, myown repressor toxin]
Increased glucose utilization in Corynebacterium glutamicum by use of maltose, and its application for the improvement of L-valine productivity. Appl. Environ. Microbiol., (76)1:370--374, January 2010. [PUMA: Bacterial Complex, Corynebacterium Dehydrogenase Glucose, Maltose, Phosphoenolpyruvate Phosphotransferase Proteins, Pyruvate Sugar System Valine, glutamicum, myown]
Studies on substrate utilisation in L-valine-producing Corynebacterium glutamicum strains deficient in pyruvate dehydrogenase complex. Bioprocess Biosyst Eng, (33)7:873--883, September 2010. [PUMA: Complex, Corynebacterium, Dehydrogenase Enhancement Genetic Pyruvate Species Specificity, Substrate Valine, myown]
Comparative 13C metabolic flux analysis of pyruvate dehydrogenase complex-deficient, L-valine-producing Corynebacterium glutamicum. Appl. Environ. Microbiol., (77)18:6644--6652, September 2011. [PUMA: Carbon Complex, Corynebacterium Dehydrogenase Dioxide, Escherichia Glycolysis, Isotopes, NADP Pathway, Pentose Phosphate Proteins, Pyruvate Transhydrogenases Valine, coli coli, glutamicum, myown]
Engineering Corynebacterium glutamicum for the production of pyruvate. Appl. Microbiol. Biotechnol., (94)2:449--459, April 2012. [PUMA: Acid, Corynebacterium Deletion, Engineering Expression, Gene Glucose, Metabolic Networks Pathways, Pyruvic Valine, and glutamicum, myown]