Publications

Cristiano Guttà, Christoph Morhard, und Markus Rehm. Applying a GAN-based classifier to improve transcriptome-based prognostication in breast cancer. PLOS Computational Biology, (19)4:1-20, Public Library of Science, April 2023. [PUMA: myown pn2 simtech izi 2023 EXC2075 morrison] URL

Daniela Stöhr, Jens O. Schmid, Tobias B. Beigl, Alexandra Mack, Daniela S. Maichl, Kai Cao, Beate Budai, Gavin Fullstone, Roland E. Kontermann, Thomas E. Mürdter, Stephen W. G. Tait, Cathrin Hagenlocher, Nadine Pollak, Peter Scheurich, und Markus Rehm. Stress-induced TRAILR2 expression overcomes TRAIL resistance in cancer cell spheroids. Cell Death & Differentiation, 2020. [PUMA: pn2 simtech izi EXC2075 2020 morrison] URL

Cristiano Guttà, Arman Rahman, Claudia Aura, Peter Dynoodt, Emilie M. Charles, Elodie Hirschenhahn, Jesuchristopher Joseph, Jasper Wouters, Ciaran de Chaumont, Mairin Rafferty, Madhuri Warren, Joost J. van den Oord, William M. Gallagher, und Markus Rehm. Low expression of pro-apoptotic proteins Bax, Bak and Smac indicates prolonged progression-free survival in chemotherapy-treated metastatic melanoma. Cell Death & Disease, (11)2:124, Nature Publishing Group, Februar 2020. [PUMA: myown pn2 simtech izi EXC2075 2020 morrison] URL

Cathrin Hagenlocher, Robin Siebert, Bruno Taschke, Senait Wieske, Angelika Hausser, und Markus Rehm. ER stress-induced cell death proceeds independently of the TRAIL-R2 signaling axis in pancreatic β cells. Cell Death Discovery, (8)1:34, 24.01.2022. [PUMA: pn2 simtech izi 2022 EXC2075 hausser morrison] URL

Vesna Vetma, Cristiano Guttà, Nathalie Peters, Christian Praetorius, Meike Hutt, Oliver Seifert, Friedegund Meier, Roland Kontermann, Dagmar Kulms, und Markus Rehm. Convergence of pathway analysis and pattern recognition predicts sensitization to latest generation TRAIL therapeutics by IAP antagonism. Cell Death & Differentiation 2020, 1--16, Nature Publishing Group, Februar 2020. [PUMA: myown pn2 simtech izi EXC2075 2020 morrison] URL

Dirke Imig, Nadine Pollak, Frank Allgöwer, und Markus Rehm. Sample-based modeling reveals bidirectional interplay between cell cycle progression and extrinsic apoptosis. PLOS Computational Biology, (16)6:1-17, Public Library of Science, Juni 2020. [PUMA: pn2 simtech izi EXC2075 2020 morrison] URL

Christian T. Hellwig, M. Eugenia Delgado, Josip Skoko, Lydia Dyck, Carol Hanna, Alexa Wentges, Claudia Langlais, Cathrin Hagenlocher, Alexandra Mack, David Dinsdale, Kelvin Cain, Marion MacFarlane, und Markus Rehm. Proteasome inhibition triggers the formation of TRAIL receptor 2 platforms for caspase-8 activation that accumulate in the cytosol. Cell Death & Differentiation 2021, 1--9, Nature Publishing Group, August 2021. [PUMA: pn2 simtech izi 2021 EXC2075 morrison] URL

Daniela Stöhr, und Markus Rehm. Linking hyperosmotic stress and apoptotic sensitivity. The FEBS Journal, febs.15520, Blackwell Publishing Ltd, August 2020. [PUMA: pn2 simtech izi EXC2075 2020 morrison] URL

Tobias B Beigl, Alexander Paul, Thomas P Fellmeth, Dang Nguyen, Lynn Barber, Sandra Weller, Benjamin Schäfer, Bernhard F Gillissen, Walter E Aulitzky, Hans-Georg Kopp, Markus Rehm, David W Andrews, Kristyna Pluhackova, und Frank Essmann. BCL-2 and BOK regulate apoptosis by interaction of their C-terminal transmembrane domains. EMBO reports, (25)9:3896-3924--3924, John Wiley & Sons, Ltd, September 2024. [PUMA: simtech izi 2024 morrison] URL

Karsten Kuritz, Daniela Stöhr, Daniela Simone Maichl, Nadine Pollak, Markus Rehm, und Frank Allgöwer. Reconstructing temporal and spatial dynamics from single-cell pseudotime using prior knowledge of real scale cell densities. Scientific Reports, (10)1:3619, Nature Publishing Group, Dezember 2020. [PUMA: pn2 simtech izi EXC2075 2020 morrison] URL