Publications

Roman Fischer, Harald Wajant, Roland Kontermann, Klaus Pfizenmaier, and Olaf Maier. Astrocyte-specific activation of TNFR2 promotes oligodendrocyte maturation by secretion of leukemia inhibitory factor. Glia, (62)2:272--283, February 2014. [PUMA: izi 2014 pfizenmaier kontermann] URL

Robert Lindner, Anna Moosmann, Alexander Dietrich, Heiner Böttinger, Roland Kontermann, and Martin Siemann-Herzberg. Process development of periplasmatically produced single chain fragment variable against epidermal growth factor receptor in Escherichia coli. Journal of Biotechnology, (192):136--145, Elsevier BV, December 2014. [PUMA: izi 2014 kontermann] URL

Mamta Jaiswal, Radovan Dvorsky, Ehsan Amin, Sarah L. Risse, Eyad K. Fansa, Si Cai Zhang, Mohamed S. Taha, Aziz R. Gauhar, Saeideh Nakhaei-Rad, Claus Kordes, Katja T. Koessmeier, Ion C. Cirstea, Monilola A. Olayioye, Dieter Häussinger, and Mohammad R. Ahmadian. Functional cross-talk between ras and rho pathways: A ras-specific gtpase-activating protein (p120RasGAP) competitively inhibits the rhogap activity of deleted in liver cancer (DLC) tumor suppressor by masking the catalytic arginine finger. Journal of Biological Chemistry, (289)10:6839--6849, March 2014. [PUMA: olayioye izi 2014] URL

David Barras, Nadja Chevalier, Vincent Zoete, Rosemary Dempsey, Karine Lapouge, Monilola A. Olayioye, Olivier Michielin, and Christian Widmann. A WXW Motif Is Required for the Anticancer Activity of the TAT-RasGAP317–326 Peptide. Journal of Biological Chemistry, (289)34:23701--23711, August 2014. [PUMA: olayioye izi 2014] URL

Oliver Seifert, Nadine Pollak, Anja Nusser, Frank Steiniger, Ronny Rüger, Klaus Pfizenmaier, and Roland E. Kontermann. Immuno-LipoTRAIL: Targeted delivery of TRAIL-functionalized liposomal nanoparticles. Bioconjugate Chemistry, (25)5:879--887, May 2014. [PUMA: izi 2014 pfizenmaier kontermann] URL

Martin Siegemund, Fabian Richter, Oliver Seifert, Felix Unverdorben, and Roland E. Kontermann. Expression and Purification of Recombinant Antibody Formats and Antibody Fusion Proteins. Methods in molecular biology (Clifton, N.J.), (1131):273--295, 2014. [PUMA: izi 2014 kontermann] URL

Philipp Diebolder, Armin Keller, Stephanie Haase, Anne Schlegelmilch, Jonathan D Kiefer, Tamana Karimi, Tobias Weber, Gerhard Moldenhauer, Roland Kehm, Anna M Eis-Hübinger, Dirk Jäger, Philippe A Federspil, Christel Herold-Mende, Gerhard Dyckhoff, Roland E Kontermann, Michaela AE Arndt, and Jürgen Krauss. Generation of “LYmph Node Derived Antibody Libraries” (LYNDAL) for selecting fully human antibody fragments with therapeutic potential. mAbs, (6)1:130-142, Taylor & Francis, 2014. [PUMA: izi 2014 kontermann] URL

Anna Moosmann, Egbert Müller, and Heiner Böttinger. Purification of PEGylated Proteins, with the example of PEGylated lysozyme and PEGylated scFv. Methods in Molecular Biology, (1129):527--538, 2014. [PUMA: boettinger izi 2014] URL

Ulrich H. Weidle, Roland E. Kontermann, and Ulrich Brinkmann. Tumor-antigen-binding bispecific antibodies for cancer treatment. Seminars in Oncology, (41)5:653--660, October 2014. [PUMA: izi 2014 kontermann] URL

Ronny Rüger, Felista L. Tansi, Markus Rabenhold, Frank Steiniger, Roland E. Kontermann, Alfred Fahr, and Ingrid Hilger. In vivo near-infrared fluorescence imaging of FAP-expressing tumors with activatable FAP-targeted, single-chain Fv-immunoliposomes. Journal of Controlled Release, (186):1--10, July 2014. [PUMA: izi 2014 kontermann] URL

V. Kermer, N. Hornig, M. Harder, A. Bondarieva, R. E. Kontermann, and D. Muller. Combining Antibody-Directed Presentation of IL-15 and 4-1BBL in a Trifunctional Fusion Protein for Cancer Immunotherapy. Molecular Cancer Therapeutics, (13)1:112--121, January 2014. [PUMA: izi 2014 mueller kontermann] URL

Bettina Huck, Stephan Duss, Angelika Hausser, and Monilola A. Olayioye. Elevated protein kinase D3 (PKD3) expression supports proliferation of Triple-negative breast cancer cells and contributes to mTORC1-S6K1 pathway activation. Journal of Biological Chemistry, (289)6:3138--3147, February 2014. [PUMA: olayioye izi 2014 hausser] URL

Simon Neumann, Jan Hasenauer, Nadine Pollak, and Peter Scheurich. Dominant negative effects of tumor necrosis factor (tnf)-related apoptosis-inducing ligand (TRAIL) receptor 4 on TRAIL receptor 1 signaling by Formation of heteromeric complexes. Journal of Biological Chemistry, (289)23:16576--16587, June 2014. [PUMA: izi 2014 scheuric] URL

Babett Oesterreich, Birgit Lorenz, Tim Schmitter, Roland Kontermann, Michael Zenn, Bastian Zimmermann, Markus Haake, Udo Lorenz, and Knut Ohlsen. Characterization of the biological anti-staphylococcal functionality of hUK-66 IgG1, ahumanized monoclonal antibody as substantial component for an immunotherapeutic approach. Human Vaccines and Immunotherapeutics, (10)4:926--937, 2014. [PUMA: izi 2014 kontermann] URL

O. Seifert, A. Plappert, S. Fellermeier, M. Siegemund, K. Pfizenmaier, and R. E. Kontermann. Tetravalent Antibody-scTRAIL Fusion Proteins with Improved Properties. Molecular Cancer Therapeutics, (13)1:101--111, January 2014. [PUMA: izi 2014 pfizenmaier kontermann] URL

Yvonne Möller, Martin Siegemund, Sven Beyes, Ricarda Herr, Daniele Lecis, Domenico Delia, Roland Kontermann, Tilman Brummer, Klaus Pfizenmaier, and Monilola A. Olayioye. EGFR-targeted TRAIL and a Smac mimetic synergize to overcome apoptosis resistance in KRAS mutant colorectal cancer cells. In John Souglakos (Eds.), PLoS ONE, (9)9:e107165, September 2014. [PUMA: olayioye izi 2014 pfizenmaier kontermann] URL

Annabell Bischoff, Bettina Huck, Bettina Keller, Michaela Strotbek, Simone Schmid, Melanie Boerries, Hauke Busch, Dafne Müller, and Monilola A. Olayioye. MiR149 functions as a tumor suppressor by controlling breast epithelial cell migration and invasion. Cancer Research, (74)18:5256--5265, September 2014. [PUMA: olayioye izi 2014] URL

Christoph Wille, Conny Köhler, Milena Armacki, Arsia Jamali, Ulrike Gössele, Klaus Pfizenmaier, Thomas Seufferlein, and Tim Eiseler. Protein kinase D2 induces invasion of pancreatic cancer cells by regulating matrix metalloproteinases.. Molecular biology of the cell, (25)3:324--36, February 2014. [PUMA: izi 2014 pfizenmaier] URL

Fabian Konrath, Johannes Witt, Thomas Sauter, and Dagmar Kulms. Identification of New IκBα Complexes by an Iterative Experimental and Mathematical Modeling Approach. In Feilim Mac Gabhann (Eds.), PLoS Computational Biology, (10)3:e1003528, March 2014. [PUMA: izi 2014 kulms] URL

Stefan Kiesgen, Nora Liebers, Martin Cremer, Ulrich Arnold, Tobias Weber, Armin Keller, Christel Herold-Mende, Gerhard Dyckhoff, Dirk Jäger, Roland E. Kontermann, Michaela A.E. Arndt, Jürgen Krauss, and Anna Wu. A fusogenic dengue virus-derived peptide enhances antitumor efficacy of an antibody-ribonuclease fusion protein targeting the EGF receptor. Protein Engineering, Design and Selection, (27)10:331--337, October 2014. [PUMA: izi 2014 kontermann] URL