Publications

Meike Hutt, Aline Färber-Schwarz, Felix Unverdorben, Fabian Richter, and Roland E. Kontermann. Plasma half-life extension of small recombinant antibodies by fusion to immunoglobulin-binding domains. Journal of Biological Chemistry, (287)7:4462--4469, February 2012. [PUMA: izi 2012 kontermann] URL

Stephan A. Eisler, Yannick F. Fuchs, Klaus Pfizenmaier, and Angelika Hausser. G-PKDrep-live, a genetically encoded FRET reporter to measure PKD activity at the trans-Golgi-network. Biotechnology Journal, (7)1:148--154, January 2012. [PUMA: izi 2012 pfizenmaier hausser] URL

Roland E. Kontermann. Dual targeting strategies with bispecific antibodies. mAbs, (4)2:182--197, March 2012. [PUMA: izi 2012 kontermann] URL

Christian Winkel, Simon Neumann, Christina Surulescu, and Peter Scheurich. A minimal mathematical model for the initial molecular interactions of death receptor signalling. Mathematical Biosciences and Engineering, (9)3:663--683, July 2012. [PUMA: izi 2012 scheuric] URL

Roland E. Kontermann. Antibody-cytokine fusion proteins. Archives of Biochemistry and Biophysics, (526)2:194--205, October 2012. [PUMA: izi 2012 kontermann] URL

Felix Unverdorben, Aline Färber-Schwarz, Fabian Richter, Meike Hutt, and Roland E. Kontermann. Half-life extension of a single-chain diabody by fusion to domain B of staphylococcal protein A. Protein Engineering, Design and Selection, (25)2:81--88, February 2012. [PUMA: izi 2012 kontermann] URL

Nora Hornig, Vanessa Kermer, Katharina Frey, Philipp Diebolder, Roland E. Kontermann, and Dafne Müller. Combination of a bispecific antibody and costimulatory antibody-ligand fusion proteins for targeted cancer immunotherapy. Journal of Immunotherapy, (35)5:418--429, June 2012. [PUMA: izi 2012 kontermann] URL

Oliver Seifert, Aline Plappert, Nadine Heidel, Sina Fellermeier, Sylvia K E Messerschmidt, Fabian Richter, and Roland E. Kontermann. The IgM CH2 domain as covalently linked homodimerization module for the generation of fusion proteins with dual specificity. Protein Engineering, Design and Selection, (25)10:603--612, October 2012. [PUMA: izi 2012 kontermann] URL

Anna Moosmann, Elke Gerlach, Robert Lindner, and Heiner Böttinger. Purification of a PEGylated single chain Fv. Journal of Chromatography A, (1236):90--96, May 2012. [PUMA: boettinger izi 2012] URL

Vanessa Kermer, Volker Baum, Nora Hornig, Roland E. Kontermann, and Dafne Müller. An Antibody Fusion Protein for Cancer Immunotherapy Mimicking IL-15 \textlessi\textgreatertrans\textless/i\textgreater -Presentation at the Tumor Site. Molecular Cancer Therapeutics, (11)6:1279--1288, June 2012. [PUMA: izi 2012 kontermann] URL

M. Siegemund, N. Pollak, O. Seifert, K. Wahl, K. Hanak, A. Vogel, A. K. Nussler, D. Göttsch, S. Münkel, H. Bantel, R. E. Kontermann, and K. Pfizenmaier. Superior antitumoral activity of dimerized targeted single-chain TRAIL fusion proteins under retention of tumor selectivity. Cell Death and Disease, (3)4:e295, April 2012. [PUMA: izi 2012 kontermann] URL

Dafne Müller. Targeted cancer immunotherapy: Mimicking physiological trans-presentation of IL-15. OncoImmunology, (1)7:1213--1214, October 2012. [PUMA: izi 2012 mueller] URL

Johanna Heering, Nicole Weis, Monika Holeiter, Felix Neugart, Annette Staebler, Tanja N. Fehm, Annabell Bischoff, Jürgen Schiller, Stephan Duss, Simone Schmid, Thomas Korte, Andreas Herrmann, and Monilola A Olayioye. Loss of the ceramide transfer protein augments EGF receptor signaling in breast cancer. Cancer Research, (72)11:2855--2866, June 2012. [PUMA: olayioye izi 2012] URL

Jan Hasenauer, Julian Heinrich, Malgorzata Doszczak, Peter Scheurich, Daniel Weiskopf, and Frank Allgöwer. A visual analytics approach for models of heterogeneous cell populations. Eurasip Journal on Bioinformatics and Systems Biology, (2012)1:4, December 2012. [PUMA: izi 2012 scheuric] URL

Monilola A. Olayioye, and Angelika Hausser. Integration of non-vesicular and vesicular transport processes at the Golgi complex by the PKD-CERT network. Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, (1821)8:1096--1103, August 2012. [PUMA: olayioye izi 2012 hausser] URL

Bettina Huck, Ralf Kemkemer, Mirita Franz-Wachtel, Boris Macek, Angelika Hausser, and Monilola A. Olayioye. GIT1 Phosphorylation on Serine 46 by PKD3 regulates paxillin trafficking and cellular protrusive activity. Journal of Biological Chemistry, (287)41:34604--34613, October 2012. [PUMA: olayioye izi 2012 hausser] URL

Mirita Franz-Wachtel, Stephan A. Eisler, Karsten Krug, Silke Wahl, Alejandro Carpy, Alfred Nordheim, Klaus Pfizenmaier, Angelika Hausser, and Boris Macek. Global Detection of Protein Kinase D-dependent Phosphorylation Events in Nocodazole-treated Human Cells. Molecular & Cellular Proteomics, (11)5:160--170, May 2012. [PUMA: izi 2012 pfizenmaier hausser] URL

G. Holeiter, A. Bischoff, A. C. Braun, B. Huck, P. Erlmann, S. Schmid, R. Herr, T. Brummer, and M. A. Olayioye. The RhoGAP protein deleted in liver cancer 3 (DLC3) is essential for adherens junctions integrity. Oncogenesis, (1)6:e13--e13, Nature Publishing Group, June 2012. [PUMA: olayioye izi 2012] URL

C. Richter, S. Messerschmidt, G. Holeiter, J. Tepperink, S. Osswald, A. Zappe, M. Branschadel, V. Boschert, D. A. Mann, P. Scheurich, and A. Krippner-Heidenreich. The Tumor Necrosis Factor Receptor Stalk Regions Define Responsiveness to Soluble versus Membrane-Bound Ligand. Molecular and Cellular Biology, (32)13:2515--2529, July 2012. [PUMA: izi 2012 scheuric] URL

Johannes Witt, Fabian Konrath, Oliver Sawodny, Michael Ederer, Dagmar Kulms, and Thomas Sauter. Analysing the role of UVB-induced translational inhibition and PP2Ac deactivation in NF-κB signalling using a minimal mathematical model. In Alexander Arlt (Eds.), PLoS ONE, (7)7:e40274, July 2012. [PUMA: sauter izi 2012 kulms] URL