Publications

S. Ziegler, T. Eiseler, R.-P. Scholz, A. Beck, G. Link, und A. Hausser. A novel protein kinase D phosphorylation site in the tumor suppressor Rab interactor 1 is critical for coordination of cell migration. Molecular Biology of the Cell, (22)5:570--580, 2011. [PUMA: izi 2011 hausser] URL

Anna Moosmann, Jessica Blath, Robert Lindner, Egbert Müller, und Heiner Böttinger. Aldehyde PEGylation kinetics: A standard protein versus a pharmaceutically relevant single chain variable fragment. Bioconjugate Chemistry, (22)8:1545--1558, 2011. [PUMA: boettinger izi 2011] URL

Roland E. Kontermann. Strategies for extended serum half-life of protein therapeutics. Current Opinion in Biotechnology, (22)6:868--876, 2011. [PUMA: izi 2011 kontermann] URL

Sandra Barisić, Anja C. Nagel, Mirita Franz-Wachtel, Boris MacEk, Anette Preiss, Gisela Link, Dieter Maier, und Angelika Hausser. Phosphorylation of ser 402 impedes phosphatase activity of slingshot 1. EMBO Reports, (12)6:527--533, 2011. [PUMA: izi 2011 hausser] URL

Roman Fischer, Olaf Maier, Matthias Naumer, Anja Krippner-Heidenreich, Peter Scheurich, und Klaus Pfizenmaier. Ligand-induced internalization of TNF receptor 2 mediated by a di-leucin motif is dispensable for activation of the NFκB pathway. Cellular Signalling, (23)1:161--170, 2011. [PUMA: izi 2011 pfizenmaier] URL

M. Hörnle, N. Peters, B. Thayaparasingham, H. Vörsmann, H. Kashkar, und D. Kulms. Caspase-3 cleaves XIAP in a positive feedback loop to sensitize melanoma cells to TRAIL-induced apoptosis. Oncogene, (30)5:575--587, 2011. [PUMA: izi 2011] URL

Jeannette Gerspach, Klaus Pfizenmaier, und Harald Wajant. Therapeutic Targeting of CD95 and the TRAIL Death Receptors. Recent Patents on Anti-Cancer Drug Discovery, (6)3:294--310, 2011. [PUMA: izi 2011 pfizenmaier] URL

Johannes Witt, Sandra Barisic, Oliver Sawodny, Michael Ederer, Dagmar Kulms, und Thomas Sauter. Modeling time delay in the NFκB signaling pathway following low dose IL-1 stimulation.. EURASIP journal on bioinformatics & systems biology, (2011)1:3, 2011. [PUMA: sauter izi 2011 kulms] URL

Jan Hasenauer, Steffen Waldherr, Malgorzata Doszczak, Nicole Radde, Peter Scheurich, und Frank Allgöwer. Identification of models of heterogeneous cell populations from population snapshot data. BMC Bioinformatics, (12):125, 2011. [PUMA: izi 2011 scheuric] URL

Monica Schliemann, Eric Bullinger, Steffen Borchers, Frank Allgöwer, Rolf Findeisen, und Peter Scheurich. Heterogeneity reduces sensitivity of cell death for TNF-Stimuli. BMC Systems Biology, (5):204, 2011. [PUMA: izi 2011 scheuric] URL

Harald Wajant, und Peter Scheurich. TNFR1-induced activation of the classical NF-κB pathway. FEBS Journal, (278)6:862--876, 2011. [PUMA: izi 2011 scheuric] URL

Klaus Pfizenmaier, und David E. Szymkowski. Workshop Summary: Introduction to Rational Design of New Means for Therapeutic Modulation of Function of the TNF Family. Adv Exp Med Biol, (691):487--491, 2011. [PUMA: izi 2011 pfizenmaier] URL

Jeannette Gerspach, Britta Schneider, Nicole Müller, Tina Otz, Harald Wajant, und Klaus Pfizenmaier. Genetic engineering of death ligands for improvement of therapeutic activity. Advances in Experimental Medicine and Biology, (691):507--519, 2011. [PUMA: izi 2011 pfizenmaier] URL

Heike Niessner, Daniela Beck, Tobias Sinnberg, Konstantinos Lasithiotakis, Evelyn MacZey, Jeannette Gogel, Sascha Venturelli, Alexander Berger, Mario Mauthe, Mahmoud Toulany, Keith Flaherty, Martin Schaller, Dirk Schadendorf, Tassula Proikas-Cezanne, Birgit Schittek, Claus Garbe, Dagmar Kulms, und Friedegund Meier. The farnesyl transferase inhibitor lonafarnib inhibits mTOR signaling and enforces sorafenib-induced apoptosis in melanoma cells. Journal of Investigative Dermatology, (131)2:468--479, 2011. [PUMA: izi 2011 kulms] URL

Roman Fischer, Olaf Maier, Martin Siegemund, Harald Wajant, Peter Scheurich, and Klaus Pfizenmaier. A TNF receptor 2 selective agonist rescues human neurons from oxidative stress-induced cell death. PLoS ONE, (6)11:e27621, 2011. [PUMA: izi 2011 pfizenmaier] URL

Julia Ranzinger, Amin Rustom, Marcus Abel, Julia Leyh, Lars Kihm, Margarete Witkowski, Peter Scheurich, Martin Zeier, and Vedat Schwenger. Nanotube action between human mesothelial cells reveals novel aspects of inflammatory responses. PLoS ONE, (6)12:e29537, 2011. [PUMA: izi 2011 scheuric] URL

Björn Krenz, Felix Neugart, Tatjana Kleinow, and Holger Jeske. Self-interaction of Abutilon mosaic virus replication initiator protein (Rep) in plant cell nuclei. Virus Research, (161)2:194--197, 2011. [PUMA: izi 2011] URL

Kornelia Ellwanger, Christine Kienzle, Sylke Lutz, Zheng‑Gen Jin, Maria T. Wiekowski, Klaus Pfizenmaier, and Angelika Hausser. Protein kinase D controls voluntary-running-induced skeletal muscle remodelling. Biochemical Journal, (440)3:327--324, 2011. [PUMA: izi 2011 pfizenmaier hausser] URL

Rolf Peter Scholz, Johan O.R. Gustafsson, Peter Hoffmann, Mamta Jaiswal, Mohammed Reza Ahmadian, Stephan A. Eisler, Patrik Erlmann, Simone Schmid, Angelika Hausser, and Monilola A. Olayioye. The tumor suppressor protein DLC1 is regulated by PKD-mediated GAP domain phosphorylation. Experimental Cell Research, (317)4:496--503, 2011. [PUMA: olayioye izi 2011 hausser] URL

M. Chertoff, N. Di Paolo, A. Schoeneberg, A. Depino, C. Ferrari, W. Wurst, K. Pfizenmaier, U. Eisel, and F. Pitossi. Neuroprotective and neurodegenerative effects of the chronic expression of tumor necrosis factor α in the nigrostriatal dopaminergic circuit of adult mice. Experimental Neurology, (227)2:237--251, Elsevier BV, Februar 2011. [PUMA: izi 2011 pfizenmaier] URL