{ "types" : { "Bookmark" : { "pluralLabel" : "Bookmarks" }, "Publication" : { "pluralLabel" : "Publications" }, "GoldStandardPublication" : { "pluralLabel" : "GoldStandardPublications" }, "GoldStandardBookmark" : { "pluralLabel" : "GoldStandardBookmarks" }, "Tag" : { "pluralLabel" : "Tags" }, "User" : { "pluralLabel" : "Users" }, "Group" : { "pluralLabel" : "Groups" }, "Sphere" : { "pluralLabel" : "Spheres" } }, "properties" : { "count" : { "valueType" : "number" }, "date" : { "valueType" : "date" }, "changeDate" : { "valueType" : "date" }, "url" : { "valueType" : "url" }, "id" : { "valueType" : "url" }, "tags" : { "valueType" : "item" }, "user" : { "valueType" : "item" } }, "items" : [ { "type" : "Publication", "id" : "https://puma.ub.uni-stuttgart.de/bibtex/295af4cf87ffa1c7f150a05deb8bb810d/inspo5", "tags" : [ "bladder","material","adaptation","biological","urinary","contraction","tissue","free","soft","properties" ], "intraHash" : "95af4cf87ffa1c7f150a05deb8bb810d", "interHash" : "ad5f2b6a3128f8eb0f36ab2826d465bb", "label" : "Shaping Smooth Muscle Forces: The Role of Preconditioning in Urinary Smooth Muscle", "user" : "inspo5", "description" : "", "date" : "2026-03-10 11:32:12", "changeDate" : "2026-03-10 11:32:12", "count" : 1, "pub-type": "article", "journal": "Journal of Applied Physiology","publisher":"American Physiological Society", "year": "2026", "url": "http://dx.doi.org/10.1152/japplphysiol.00782.2025", "author": [ "Simon Kiem","Stefan Papenkort","Mischa Borsdorf","Markus Böl","Tobias Siebert" ], "authors": [ {"first" : "Simon", "last" : "Kiem"}, {"first" : "Stefan", "last" : "Papenkort"}, {"first" : "Mischa", "last" : "Borsdorf"}, {"first" : "Markus", "last" : "Böl"}, {"first" : "Tobias", "last" : "Siebert"} ], "editor": [ "Tobias Siebert" ], "editors": [ {"first" : "Tobias", "last" : "Siebert"} ], "abstract": "Smooth muscle (SM) exhibits rapid mechanical adaptation in response to various stimuli, posing challenges for reproducible experimental results and consistent material parameter determination in biomechanical modeling. Preconditioning involving repeated loading and unloading cycles are commonly used to stabilize mechanical responses prior to testing. However, their influence on tissue properties and data variability remains underexplored. This study compares the effects of three preconditioning routines \u2013 passive cycling (PCYC), no preconditioning (PNPC), and free contraction (PFC) \u2013 on the active and passive force responses of porcine urinary bladder (UB) SM tissue. Three tissue strips from 12 UBs were randomly assigned to one of the routines and underwent an identical protocol involving a passive stretch ramp and two isometric contractions (IC1, IC2) to evaluate active and passive force development. After PCYC, the tissue generated the highest active (IC2: 44.7 ± 29.4 kPa) and passive tensions (IC2: 5.6 ± 4.3 kPa), though it also showed the highest variance in active tension. PNPC resulted in the lowest variance in active tension with a coefficient of variation (CV) of 45%, and PFC showed the lowest variance in passive tension, CV = 57%. These findings imply that the decision for a certain preconditioning protocol influences the observed mechanical properties. In this context, PFC appears promising for minimizing passive force variability and preventing creep-induced lengthening. This could offer a more reliable foundation for subsequent experiments analyzing mechanical parameters. This study underscores the importance of customized preconditioning strategies to enhance consistency and comparability in SM research and organ modeling.", "language" : "English", "issn" : "1522-1601", "preprinturl" : "https://journals.physiology.org/doi/abs/10.1152/japplphysiol.00782.2025", "doi" : "10.1152/japplphysiol.00782.2025", "bibtexKey": "Kiem_2026" } , { "type" : "Publication", "id" : "https://puma.ub.uni-stuttgart.de/bibtex/21c09ad3a57d45986105107c77d0da5cf/inspo5", "tags" : [ "3d","image","fibres","shape","muscle","deformation","processing","contraction","dynamic","movement","ultrasound" ], "intraHash" : "1c09ad3a57d45986105107c77d0da5cf", "interHash" : "539e1f9768e937f368f3546f4de55813", "label" : "Determination of muscle shape deformations of the tibialis anterior during dynamic contractions using 3D ultrasound", "user" : "inspo5", "description" : "", "date" : "2024-07-05 14:59:56", "changeDate" : "2024-07-18 11:02:59", "count" : 7, "pub-type": "article", "journal": "Frontiers in Bioengineering and Biotechnology", "year": "2024", "url": "https://www.frontiersin.org/articles/10.3389/fbioe.2024.1388907", "author": [ "Annika S. Sahrmann","Lukas Vosse","Tobias Siebert","Geoffrey G. Handsfield","Oliver Röhrle" ], "authors": [ {"first" : "Annika S.", "last" : "Sahrmann"}, {"first" : "Lukas", "last" : "Vosse"}, {"first" : "Tobias", "last" : "Siebert"}, {"first" : "Geoffrey G.", "last" : "Handsfield"}, {"first" : "Oliver", "last" : "Röhrle"} ], "volume": "12", "issn" : "2296-4185", "doi" : "10.3389/fbioe.2024.1388907", "bibtexKey": "Sahrmann2024c" } , { "type" : "Publication", "id" : "https://puma.ub.uni-stuttgart.de/bibtex/21947549f0f7295e064e79f467f085d7b/inspo5", "tags" : [ "3D","image","muscle","deformation","processing","contraction","dynamic","movement","ultrasound" ], "intraHash" : "1947549f0f7295e064e79f467f085d7b", "interHash" : "277676c63d8a348032cb6102b6abeb37", "label" : "Determination of muscle shape deformations of the tibialis anterior during dynamic contractions using 3D ultrasound.\r\nFront. Bioeng. Biotechnol. 12:1388907.", "user" : "inspo5", "description" : "", "date" : "2024-06-05 15:26:27", "changeDate" : "2024-07-16 12:38:53", "count" : 3, "pub-type": "article", "journal": "Frontiers in Bioengineering and Biotechnology", "year": "2024", "url": "https://www.frontiersin.org/articles/10.3389/fbioe.2024.1388907/full?&utm_source=Email_to_authors_&utm_medium=Email&utm_content=T1_11.5e1_author&utm_campaign=Email_publication&field=&journalName=Frontiers_in_Bioengineering_and_Biotechnology&id=1388907", "editor": [ "Tobias Siebert" ], "editors": [ {"first" : "Tobias", "last" : "Siebert"} ], "volume": "12","abstract": "Purpose: In this paper, we introduce a novel method for determining 3D deformations of the human tibialis anterior (TA) muscle during dynamic movements using 3D ultrasound.\r\n\r\nMaterials and Methods: An existing automated 3D ultrasound system is used for data acquisition, which consists of three moveable axes, along which the probe can move. While the subjects perform continuous plantar- and dorsiflexion movements in two different controlled velocities, the ultrasound probe sweeps cyclically from the ankle to the knee along the anterior shin. The ankle joint angle can be determined using reflective motion capture markers. Since we considered the movement direction of the foot, i.e., active or passive TA, four conditions occur: slow active, slow passive, fast active, fast passive. By employing an algorithm which defines ankle joint angle intervals, i.e., intervals of range of motion (ROM), 3D images of the volumes during movement can be reconstructed.\r\n\r\nResults: We found constant muscle volumes between different muscle lengths, i.e., ROM intervals. The results show an increase in mean cross-sectional area (CSA) for TA muscle shortening. Furthermore, a shift in maximum CSA towards the proximal side of the muscle could be observed for muscle shortening. We found significantly different maximum CSA values between the fast active and all other conditions, which might be caused by higher muscle activation due to the faster velocity.\r\n\r\nConclusion: In summary, we present a method for determining muscle volume deformation during dynamic contraction using ultrasound, which will enable future empirical studies and 3D computational models of skeletal muscles.", "language" : "English", "doi" : "10.3389/fbioe.2024.1388907", "bibtexKey": "siebert2024determination" } , { "type" : "Publication", "id" : "https://puma.ub.uni-stuttgart.de/bibtex/288f633199ed2d6814a99626939d3d01b/inspo5", "tags" : [ "surface","isometric","voluntary","maximal","muscles","s","electromyography","PFM","pelvic","MVC","contraction","floor","EMG" ], "intraHash" : "88f633199ed2d6814a99626939d3d01b", "interHash" : "daa15e055c72f0862fdcf0dab766cd8b", "label" : "Intraday and interday reliability of pelvic floor muscles electromyography in continent woman. Neurourol Urodyn", "user" : "inspo5", "description" : "", "date" : "2022-07-19 11:10:29", "changeDate" : "2022-07-19 09:10:56", "count" : 1, "pub-type": "article", "journal": "Wiley Online Library Neurourology and Urodynamics", "year": "2020", "url": "", "editor": [ "Tobias Siebert" ], "editors": [ {"first" : "Tobias", "last" : "Siebert"} ], "volume": "39","number": "1","pages": "271-278","abstract": "Aims\nVaginal surface electromyography (sEMG) is a tool used for the diagnosis and therapeutic intervention of urinary incontinence. Current sEMG systems differ in regard to electrode arrangement and data reproducibility. The aim of this study was to determine the intrasession, intraday, and interday reliabilities of sEMG parameters using a probe with circumferential electrode-position.\n\nMethods\nThe intrasession, intraday, and interday reliabilities of maximum isometric voluntary contractions (MVC) of the pelvic floor muscles were assessed for 19 healthy continent women. Three sEMG parameters that are used to describe muscle activity were verified: maximal EMG (EMGmax), mean over 500\u2009ms around EMGmax (EMGA0.5), and mean over 2\u2009seconds during MVC plateau (EMGA2-4). Relative and absolute reliability parameters were calculated, and the statistical methods described by Bland and Altman were applied to the data.\n\nResults\nWe observed substantial reliabilities for all obtained parameters (EMGmax, EMGA2-4, and EMGA0.5) in regard to the intrasession measurements (ICC\u2009=\u20090.93-0.97; CI\u2009=\u20090.86-0.99). Overall, the intraday reliability has been moderate (ICC\u2009=\u20090.64-0.75; CI\u2009=\u20090.27-0.90). EMGmax (ICC\u2009=\u20090.75; CI\u2009=\u20090.45-0.90) and EMGA2-4 (ICC\u2009=\u20090.73, CI\u2009=\u20090.42-0.89) were higher than EMGA0.5 (ICC\u2009=\u20090.64; CI\u2009=\u20090.27-0.85). However, the interday reliability was only fair for EMGmax (ICC\u2009=\u20090.48; CI\u2009=\u20090.04-0.77) and EMGA0.5 (ICC\u2009=\u20090.51; CI\u2009=\u20090.07-0.78) but moderate for EMGA2-4 (ICC\u2009=\u20090.65; CI\u2009=\u20090.28-0.85).\n\nConclusions\nThis intrasession, intraday, and interday reliability results are similar to the results reported in the literature using probes with longitudinally oriented bars. The mean sEMG signal over 2\u2009seconds (EMGA2-4) exhibited the highest reliability and is recommended for further studies. The interday reliability might be enhanced by considering the menstruation cycle.", "doi" : "https://doi.org/10.1002/nau.24187", "bibtexKey": "siebert2020intraday" } , { "type" : "Publication", "id" : "https://puma.ub.uni-stuttgart.de/bibtex/2f3554c02f79ed324fdf1437e5be63b62/inspo5", "tags" : [ "exercise","plyometric","enhancement","history","reflex","passive","performance","stretch","energy","dependence","elastic","contraction","eccentric" ], "intraHash" : "f3554c02f79ed324fdf1437e5be63b62", "interHash" : "52bab2525454ad268d0bb12e8879eb69", "label" : "Editorial: The Stretch-Shortening Cycle of Active Muscle and Muscle-Tendon Complex: What, Why and How It Increases Muscle Performance?", "user" : "inspo5", "description" : "", "date" : "2022-07-19 11:10:29", "changeDate" : "2022-07-19 09:10:56", "count" : 2, "pub-type": "article", "journal": "Frontiers in Physiology","publisher":"Frontiers Media SA", "year": "2021", "url": "https://doi.org/10.3389%2Ffphys.2021.693141", "author": [ "Wolfgang Seiberl","Daniel Hahn","Geoffrey A. Power","Jared R. Fletcher","Tobias Siebert" ], "authors": [ {"first" : "Wolfgang", "last" : "Seiberl"}, {"first" : "Daniel", "last" : "Hahn"}, {"first" : "Geoffrey A.", "last" : "Power"}, {"first" : "Jared R.", "last" : "Fletcher"}, {"first" : "Tobias", "last" : "Siebert"} ], "editor": [ "Tobias Siebert" ], "editors": [ {"first" : "Tobias", "last" : "Siebert"} ], "volume": "12", "doi" : "10.3389/fphys.2021.693141", "bibtexKey": "Seiberl_2021" } , { "type" : "Publication", "id" : "https://puma.ub.uni-stuttgart.de/bibtex/29d530f5c074dc9af0e1c475c6ea3ca48/inspo5", "tags" : [ "sonography","dynamics","muscle","load","transverse","contraction","architecture","compression","ultrasound" ], "intraHash" : "9d530f5c074dc9af0e1c475c6ea3ca48", "interHash" : "7bc93b91d4afa86288032a24d5ee4708", "label" : "The Effect of Multidirectional Loading on Contractions of the M. Medial Gastrocnemius", "user" : "inspo5", "description" : "", "date" : "2022-07-19 11:10:29", "changeDate" : "2022-07-19 09:10:56", "count" : 2, "pub-type": "article", "journal": "Frontiers in Physiology","publisher":"Frontiers Media SA", "year": "2021", "url": "https://doi.org/10.3389%2Ffphys.2020.601799", "author": [ "David S. Ryan","Norman Stutzig","Andreas Helmer","Tobias Siebert","James M. Wakeling" ], "authors": [ {"first" : "David S.", "last" : "Ryan"}, {"first" : "Norman", "last" : "Stutzig"}, {"first" : "Andreas", "last" : "Helmer"}, {"first" : "Tobias", "last" : "Siebert"}, {"first" : "James M.", "last" : "Wakeling"} ], "editor": [ "Tobias Siebert" ], "editors": [ {"first" : "Tobias", "last" : "Siebert"} ], "volume": "11", "doi" : "10.3389/fphys.2020.601799", "bibtexKey": "Ryan_2021" } , { "type" : "Publication", "id" : "https://puma.ub.uni-stuttgart.de/bibtex/2691e2845166a4110b43d947ceaa1c0ac/inspo5", "tags" : [ "Skill","Limb","muscle","Eccentric","contraction","biomechanics","Dog","Jumping","stiffness" ], "intraHash" : "691e2845166a4110b43d947ceaa1c0ac", "interHash" : "b03343a1fd3237294b7eb8d42fe378f1", "label" : "Limb dynamics in agility jumps of beginner and advanced dogs", "user" : "inspo5", "description" : "", "date" : "2022-07-19 11:10:29", "changeDate" : "2022-07-19 09:10:56", "count" : 2, "pub-type": "article", "journal": "Journal of Experimental Biology","publisher":"The Company of Biologists", "year": "2020", "url": "https://doi.org/10.1242%2Fjeb.202119", "author": [ "Katja Söhnel","Christian Rode","Marc H. E. de Lussanet","Heiko Wagner","Martin S. Fischer","Emanuel Andrada" ], "authors": [ {"first" : "Katja", "last" : "Söhnel"}, {"first" : "Christian", "last" : "Rode"}, {"first" : "Marc H. E.", "last" : "de Lussanet"}, {"first" : "Heiko", "last" : "Wagner"}, {"first" : "Martin S.", "last" : "Fischer"}, {"first" : "Emanuel", "last" : "Andrada"} ], "editor": [ "Tobias Siebert" ], "editors": [ {"first" : "Tobias", "last" : "Siebert"} ], "doi" : "10.1242/jeb.202119", "bibtexKey": "S_hnel_2020" } ] }