{ "types" : { "Bookmark" : { "pluralLabel" : "Bookmarks" }, "Publication" : { "pluralLabel" : "Publications" }, "GoldStandardPublication" : { "pluralLabel" : "GoldStandardPublications" }, "GoldStandardBookmark" : { "pluralLabel" : "GoldStandardBookmarks" }, "Tag" : { "pluralLabel" : "Tags" }, "User" : { "pluralLabel" : "Users" }, "Group" : { "pluralLabel" : "Groups" }, "Sphere" : { "pluralLabel" : "Spheres" } }, "properties" : { "count" : { "valueType" : "number" }, "date" : { "valueType" : "date" }, "changeDate" : { "valueType" : "date" }, "url" : { "valueType" : "url" }, "id" : { "valueType" : "url" }, "tags" : { "valueType" : "item" }, "user" : { "valueType" : "item" } }, "items" : [ { "type" : "Publication", "id" : "https://puma.ub.uni-stuttgart.de/bibtex/2d4c6f9a31ee0320fc3be6307a85d6c4e/inspo5", "tags" : [ "Titin","Simtech","muscle","Contractile","Stretch","physiology","Muscle","behaviour","Sarcomere","Skeletal" ], "intraHash" : "d4c6f9a31ee0320fc3be6307a85d6c4e", "interHash" : "c1587910394340ebda12596b663f7b66", "label" : "Eccentric muscle contractions : from single muscle fibre to whole muscle mechanics", "user" : "inspo5", "description" : "", "date" : "2025-02-03 10:48:28", "changeDate" : "2025-02-03 11:10:28", "count" : 5, "pub-type": "article", "journal": "Pflügers Archiv","publisher":"Springer", "year": "2023", "url": "", "author": [ "André Tomalka" ], "authors": [ {"first" : "André", "last" : "Tomalka"} ], "volume": "475","pages": "421-435","abstract": "Eccentric muscle loading encompasses several unique features compared to other types of contractions. These features include increased force, work, and performance at decreased oxygen consumption, reduced metabolic cost, improved energy efficiency, as well as decreased muscle activity. This review summarises explanatory approaches to long-standing questions in terms of muscular contraction dynamics and molecular and cellular mechanisms underlying eccentric muscle loading. Moreover, this article intends to underscore the functional link between sarcomeric components, emphasising the fundamental role of titin in skeletal muscle. The giant filament titin reveals versatile functions ranging from sarcomere organisation and maintenance, providing passive tension and elasticity, and operates as a mechanosensory and signalling platform. Structurally, titin consists of a viscoelastic spring segment that allows activation-dependent coupling to actin. This titin-actin interaction can explain linear force increases in active lengthening experiments in biological systems. A three-filament model of skeletal muscle force production (mediated by titin) is supposed to overcome significant deviations between experimental observations and predictions by the classic sliding-filament and cross-bridge theories. Taken together, this review intends to contribute to a more detailed understanding of overall muscle behaviour and force generation\u2014from a microscopic sarcomere level to a macroscopic multi-joint muscle level\u2014impacting muscle modelling, the understanding of muscle function, and disease.", "issn" : "1432-2013", "language" : "eng", "doi" : "10.1007/s00424-023-02794-z", "bibtexKey": "tomalka2023eccentric" } , { "type" : "Publication", "id" : "https://puma.ub.uni-stuttgart.de/bibtex/232079559e33f1e8958126981cee1b324/inspo5", "tags" : [ "myown","biologie","myosin","physiology","structure","actin","PN2-8","muscle","titin","sceletal","fibre" ], "intraHash" : "32079559e33f1e8958126981cee1b324", "interHash" : "bd00323910b3bdf30e8ce2268da8c50c", "label" : "Structurally motivated models to explain the muscle\u2019s force-length relationship", "user" : "inspo5", "description" : "", "date" : "2023-11-20 14:42:45", "changeDate" : "2023-12-01 17:12:16", "count" : 5, "pub-type": "article", "journal": "Biophys. Journal 1", "year": "2023", "url": "https://www.sciencedirect.com/science/article/abs/pii/S0006349523003387?via%3Dihub", "author": [ "Rode Christian","Tomalka Andre","Blickhan R.","Siebert Tobias" ], "authors": [ {"first" : "Rode", "last" : "Christian"}, {"first" : "Tomalka", "last" : "Andre"}, {"first" : "Blickhan", "last" : "R."}, {"first" : "Siebert", "last" : "Tobias"} ], "volume": "122","number": "17","pages": "3541-3543","abstract": "Section snippets\r\nThe Rode model's explanation of the FLR's ascending limb allegedly involves pushing forces in thin filaments\r\nThe main Rockenfeller et al. argument to dismiss the Rode model is the wrong assertion that the Rode model describes the FLR\u2019s ascending limb based on pushing or compressive forces in thin filaments. The thin filaments would be too soft to transmit relevant pushing forces. However, in the Rode model, thin filaments are always pulled away from the Z-disk.\r\n\r\nFurthermore, Rockenfeller et al. wrongly assert that swXBs generate pushing forces on thin filaments in the Rode model and that the\r\n\r\nThe Rockenfeller model ignores geometrical changes developing on the FLR\u2019s ascending limb\r\nThe Rockenfeller model assumes a hexagonal filament lattice as in optimal overlap down to 0.4-μm half-sarcomere length (with about 1 μm being the optimal length) and that the lattice distances progressively increase with shortening due to volume constancy. These assumptions ignore several geometrical changes in the half-sarcomere that occur during shortening and hamper the predictive power of the model in the range of the FLR\u2019s ascending limb. For example, the Rockenfeller model predicts noThe Rockenfeller model assumes effective force in the region of double thin-filament overlap\r\nDouble thin-filament overlap starts to develop when thin filaments slide through the M-line near optimal half-sarcomere length (left-hand side of the FLR plateau). The Rockenfeller model assumes that XBs are formed in the region of double thin-filament overlap. This assumption leads to effective force in this region and cannot explain Trombitás and Tigyi-Sebes\u2019 experiments (8).\r\n\r\nTrombitás and Tigyi-Sebes stretched rigor muscle fibers leading to the detachment of thin filaments from the Z-disk.\r\n\r\nThe Rockenfeller model's effective overlap function is mechanically inconsistent on the FLR's ascending limb\r\nOne basis of the Rockenfeller model\u2019s force calculation is the effective filament overlap, the theoretical capacity to produce isometric force depending on half-sarcomere length without effects of interfilament spacing. Surprisingly, the effective filament overlap (their Figure 1 in (3)) is straight at about 0.8-μm half-sarcomere length. First, when thick-filament tips slide through the Z-disk at this length, the myosin heads meet thin filaments of opposite polarity and form swXBs in their", "language" : "English", "doi" : "10.1016/j.bpj.2023.05.026", "bibtexKey": "noauthororeditor" } , { "type" : "Publication", "id" : "https://puma.ub.uni-stuttgart.de/bibtex/21478bcee911cc1bd986507ee4394ed92/inspo5", "tags" : [ "system","Physiology","Musculoskeletal" ], "intraHash" : "1478bcee911cc1bd986507ee4394ed92", "interHash" : "5ab9f68e8c6f6627e1fba64e5170fc51", "label" : "Electromyographic activity of the vastus medialis and gastrocnemius implicates a slow stretch-shortening cycle during rowing in the field", "user" : "inspo5", "description" : "", "date" : "2022-07-19 11:10:29", "changeDate" : "2022-07-19 09:10:56", "count" : 2, "pub-type": "article", "journal": "Scientific Reports", "year": "2020", "url": "https://doi.org/10.1038/s41598-020-66124-4", "author": [ "Steffen Held","Tobias Siebert","Lars Donath" ], "authors": [ {"first" : "Steffen", "last" : "Held"}, {"first" : "Tobias", "last" : "Siebert"}, {"first" : "Lars", "last" : "Donath"} ], "editor": [ "Tobias Siebert" ], "editors": [ {"first" : "Tobias", "last" : "Siebert"} ], "volume": "10","number": "1","pages": "9451","abstract": "The consideration of the temporal and electromyographic (EMG) characteristics of stretch-shortening cycles (SSC) are crucial for the conceptualization of discipline-specific testing and training. Since leg muscles are first stretched (eccentric) and then contracted (concentric) during rowing, it can be assumed that the entire muscle tendon complex performs a SSC. Thus, it should be elucidated whether the rowing cycle can be attributed to either a slow or fast SSC. Therefore, EMG of the vastus medialis and gastrocnemius were captured (nþinspace=þinspace10, 22.8þinspace±þinspace3.1 years, 190þinspace±þinspace6þinspacecm, 82.1þinspace±þinspace9.8þinspacekg) during (single scull) rowing and subsequently compared to typical slow (countermovement jump, CMJ) and fast (drop jump, DJ) SSCs. The elapsed time between the EMG onset and the start of the eccentric phase was monitored. The pre-activation phase (PRE, before the start of the eccentric phase) and the reflex-induced activation phase (RIA 30--120þinspacems after the start of the eccentric phase) have been classified. Notable muscular activity was observed during DJ before the start of the eccentric phase (PRE) as well as during RIA. In contrast, neither CMJ nor rowing revealed any EMG-activity in these two phases. Interestingly, CMJ and race-specific rowing showed an EMG-onset during the eccentric phase. We conclude that rowing is more attributable to a slow SSC and implies that fast SSC does not reflect discipline specific muscle action and could hamper rowing-performance-enhancement.", "issn" : "2045-2322", "doi" : "10.1038/s41598-020-66124-4", "bibtexKey": "Held2020" } , { "type" : "Publication", "id" : "https://puma.ub.uni-stuttgart.de/bibtex/2be08e61de3113da4cc1cef1d0babe7eb/inspo5", "tags" : [ "Biomechanics","strength","physiology","training","musculoskeletal" ], "intraHash" : "be08e61de3113da4cc1cef1d0babe7eb", "interHash" : "98535cbd4e2b7deff05774f7b2d33b99", "label" : "Changes in mechanical power output in rowing by varying stroke rate and gearing", "user" : "inspo5", "description" : "", "date" : "2022-07-19 11:10:29", "changeDate" : "2022-07-19 09:10:56", "count" : 1, "pub-type": "article", "journal": "European Journal of Sport Science","publisher":"Routledge", "year": "2020", "url": "/brokenurl# https://doi.org/10.1080/17461391.2019.1628308 ", "author": [ "Steffen Held","Tobias Siebert","Lars Donath" ], "authors": [ {"first" : "Steffen", "last" : "Held"}, {"first" : "Tobias", "last" : "Siebert"}, {"first" : "Lars", "last" : "Donath"} ], "editor": [ "Tobias Siebert" ], "editors": [ {"first" : "Tobias", "last" : "Siebert"} ], "volume": "20","number": "3","pages": "357-365","note": "PMID: 31232195","abstract": "Abstract Each stretch-shortening-cycle (SSC) in elite sports (e.g. jumping, cycling), is characterised by utilising optimal movement-parameters (e.g. muscle shortening velocity), for maximum power (jump height, cycle velocity). It is however unclear if relevant SSC movement-parameters in rowing, such as stroke rate and gearing, have to be maximised to obtain maximum power output or if an optimum relation emerges. Thus, we measured rowing-power (Prow), leg-power (Pleg) and work-per-stroke (WPS) at of varying stroke rates (20\u201345\u2005spm), gearings (lever-changes 0.87\u20130.90\u2005m) and drag factors (100\u2013180\u2005Ws3/m3) during rowing. Experienced sub-elite young athletes performed sprint-series on (single scull, n\u2009=\u200969, 20\u2009±\u20092 years, 186\u2009±\u20097\u2005cm, 84\u2009±\u20099\u2005kg) and off the water (rowing-ergometer, n\u2009=\u200930, 19\u2009±\u20093 years, 185\u2009±\u200911\u2005cm, 77\u2009±\u200919\u2005kg). Prow increased with stroke rate for ergometer-test (r\u2009=\u20090.97, p\u2009<\u20090.001) and boat measurement (r\u2009=\u20090.98, p\u2009<\u20090.001) by 2.7\\%/stroke and 4.4\\%/stroke, respectively. Interestingly, stroke rate had a high impact on WPS (r\u2009=\u20090.79, p\u2009<\u20090.001) during boat measurement, compared to no (or specifically no high) impact on WPS (r\u2009=\u2009−0.10, p\u2009=\u20090.166) during ergometer-measurements. Drag factor (ergometer: r\u2009=\u20090.83, p\u2009<\u20090.001) and gearing (boat: r\u2009=\u20090.60, p\u2009<\u20090.001) yielded moderate to high correlations to Prow. These results indicate that no optimum stroke rate, gearing and drag factor exist for maximum power in rowing (sprint-measurement-range). Accordingly, the measurements yielded maximum power for maximum stroke rate, gearing, and drag factor.", "eprint" : "https://doi.org/10.1080/17461391.2019.1628308", "doi" : "10.1080/17461391.2019.1628308", "bibtexKey": "doi:10.1080/17461391.2019.1628308" } , { "type" : "Publication", "id" : "https://puma.ub.uni-stuttgart.de/bibtex/20f3b15cf045e74d9f0ecc98682c3f04d/mariawirzberger", "tags" : [ "myown","speech","cognition","load","physiology","learning","performance" ], "intraHash" : "0f3b15cf045e74d9f0ecc98682c3f04d", "interHash" : "2af538801cbfe9473d945f63c0f851d0", "label" : "Cognitive load influences performance, speech and physiological parameters in a multimodal dual-task setting", "user" : "mariawirzberger", "description" : "", "date" : "2020-03-20 16:22:37", "changeDate" : "2020-03-20 15:30:27", "count" : 1, "pub-type": "inproceedings", "booktitle": "Abstracts of the 60th Conference of Experimental Psychologists","publisher":"Pabst Science Publishers","address":"Lengerich", "year": "2018", "url": "", "author": [ "Maria Wirzberger","Robert Herms","Shirin Esmaeili Bijarsari","Günter Daniel Rey","Maximilian Eibl" ], "authors": [ {"first" : "Maria", "last" : "Wirzberger"}, {"first" : "Robert", "last" : "Herms"}, {"first" : "Shirin", "last" : "Esmaeili Bijarsari"}, {"first" : "Günter Daniel", "last" : "Rey"}, {"first" : "Maximilian", "last" : "Eibl"} ], "editor": [ "Alexander C. Schütz","Anna Schubö","Dominik Endres","Harald Lachnit" ], "editors": [ {"first" : "Alexander C.", "last" : "Schütz"}, {"first" : "Anna", "last" : "Schubö"}, {"first" : "Dominik", "last" : "Endres"}, {"first" : "Harald", "last" : "Lachnit"} ], "pages": "296", "bibtexKey": "Wirzberger2018TeaP" } , { "type" : "Publication", "id" : "https://puma.ub.uni-stuttgart.de/bibtex/284609c8f7d27098af12f1ffb3435a1d0/mariawirzberger", "tags" : [ "myown","speech","cognition","load","dual-task","physiology","learning","performance" ], "intraHash" : "84609c8f7d27098af12f1ffb3435a1d0", "interHash" : "a813de39fdb115c559c9b26d7cc249fd", "label" : "Influences of cognitive load on learning performance, speech and physiological parameters in a dual-task setting", "user" : "mariawirzberger", "description" : "", "date" : "2020-03-20 16:22:37", "changeDate" : "2020-03-20 15:29:13", "count" : 1, "pub-type": "inproceedings", "booktitle": "Abstracts of the 20th Conference of the European Society for Cognitive Psychology","address":"Potsdam, Germany", "year": "2017", "url": "", "author": [ "Maria Wirzberger","Robert Herms","Shirin Esmaeili Bijarsari","Günter Daniel Rey","Maximilian Eibl" ], "authors": [ {"first" : "Maria", "last" : "Wirzberger"}, {"first" : "Robert", "last" : "Herms"}, {"first" : "Shirin", "last" : "Esmaeili Bijarsari"}, {"first" : "Günter Daniel", "last" : "Rey"}, {"first" : "Maximilian", "last" : "Eibl"} ], "pages": "161", "bibtexKey": "Wirzberger2017ESCoP" } ] }