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         "type" : "Publication",
         "id"   : "https://puma.ub.uni-stuttgart.de/bibtex/295af4cf87ffa1c7f150a05deb8bb810d/inspo5",         
         "tags" : [
            "bladder","material","adaptation","biological","urinary","contraction","tissue","free","soft","properties"
         ],
         
         "intraHash" : "95af4cf87ffa1c7f150a05deb8bb810d",
         "interHash" : "ad5f2b6a3128f8eb0f36ab2826d465bb",
         "label" : "Shaping Smooth Muscle Forces: The Role of Preconditioning in Urinary Smooth Muscle",
         "user" : "inspo5",
         "description" : "",
         "date" : "2026-03-10 11:32:12",
         "changeDate" : "2026-03-10 11:32:12",
         "count" : 1,
         "pub-type": "article",
         "journal": "Journal of Applied Physiology","publisher":"American Physiological Society",
         "year": "2026", 
         "url": "http://dx.doi.org/10.1152/japplphysiol.00782.2025", 
         
         "author": [ 
            "Simon Kiem","Stefan Papenkort","Mischa Borsdorf","Markus Böl","Tobias Siebert"
         ],
         "authors": [
         	
            	{"first" : "Simon",	"last" : "Kiem"},
            	{"first" : "Stefan",	"last" : "Papenkort"},
            	{"first" : "Mischa",	"last" : "Borsdorf"},
            	{"first" : "Markus",	"last" : "Böl"},
            	{"first" : "Tobias",	"last" : "Siebert"}
         ],
         
         "editor": [ 
            "Tobias Siebert"
         ],
         "editors": [
         	
            	{"first" : "Tobias",	"last" : "Siebert"}
         ],
         "abstract": "Smooth muscle (SM) exhibits rapid mechanical adaptation in response to various stimuli, posing challenges for reproducible experimental results and consistent material parameter determination in biomechanical modeling. Preconditioning involving repeated loading and unloading cycles are commonly used to stabilize mechanical responses prior to testing. However, their influence on tissue properties and data variability remains underexplored. This study compares the effects of three preconditioning routines \u2013 passive cycling (PCYC), no preconditioning (PNPC), and free contraction (PFC) \u2013 on the active and passive force responses of porcine urinary bladder (UB) SM tissue. Three tissue strips from 12 UBs were randomly assigned to one of the routines and underwent an identical protocol involving a passive stretch ramp and two isometric contractions (IC1, IC2) to evaluate active and passive force development. After PCYC, the tissue generated the highest active (IC2: 44.7 ± 29.4 kPa) and passive tensions (IC2: 5.6 ± 4.3 kPa), though it also showed the highest variance in active tension. PNPC resulted in the lowest variance in active tension with a coefficient of variation (CV) of 45%, and PFC showed the lowest variance in passive tension, CV = 57%. These findings imply that the decision for a certain preconditioning protocol influences the observed mechanical properties. In this context, PFC appears promising for minimizing passive force variability and preventing creep-induced lengthening. This could offer a more reliable foundation for subsequent experiments analyzing mechanical parameters. This study underscores the importance of customized preconditioning strategies to enhance consistency and comparability in SM research and organ modeling.",
         "language" : "English",
         
         "issn" : "1522-1601",
         
         "preprinturl" : "https://journals.physiology.org/doi/abs/10.1152/japplphysiol.00782.2025",
         
         "doi" : "10.1152/japplphysiol.00782.2025",
         
         "bibtexKey": "Kiem_2026"

      }
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         "type" : "Publication",
         "id"   : "https://puma.ub.uni-stuttgart.de/bibtex/23cb83562fd4a436e376d28712fe58a37/mhartmann",         
         "tags" : [
            "simulation;","Real-time","models","system;","Material","dynamic","vorlaeufig","flow","System"
         ],
         
         "intraHash" : "3cb83562fd4a436e376d28712fe58a37",
         "interHash" : "f49a945ea15206c6cd60d4db77a8d5a5",
         "label" : "System Dynamic Models and Real-time Simulation of Complex Material\n\tFlow Systems",
         "user" : "mhartmann",
         "description" : "",
         "date" : "2018-07-20 10:54:15",
         "changeDate" : "2018-07-20 08:54:15",
         "count" : 2,
         "pub-type": "incollection",
         "booktitle": "Enabling Manufacturing Competitiveness and Economic Sustainability","publisher":"Springer Berlin Heidelberg",
         "year": "2012", 
         "url": "http://dx.doi.org/10.1007/978-3-642-23860-4_52", 
         
         "author": [ 
            "S. Hoher","P. Schindler","S. G?ttlich","V. Schleper","S. Röck"
         ],
         "authors": [
         	
            	{"first" : "S.",	"last" : "Hoher"},
            	{"first" : "P.",	"last" : "Schindler"},
            	{"first" : "S.",	"last" : "G?ttlich"},
            	{"first" : "V.",	"last" : "Schleper"},
            	{"first" : "S.",	"last" : "Röck"}
         ],
         
         "editor": [ 
            "Hoda A. ElMaraghy"
         ],
         "editors": [
         	
            	{"first" : "Hoda A.",	"last" : "ElMaraghy"}
         ],
         "pages": "316-321",
         "isbn" : "978-3-642-23859-8",
         
         "owner" : "schleper",
         
         "language" : "English",
         
         "doi" : "10.1007/978-3-642-23860-4_52",
         
         "bibtexKey": "hoher2012system"

      }
	  
   ]
}