{ "types" : { "Bookmark" : { "pluralLabel" : "Bookmarks" }, "Publication" : { "pluralLabel" : "Publications" }, "GoldStandardPublication" : { "pluralLabel" : "GoldStandardPublications" }, "GoldStandardBookmark" : { "pluralLabel" : "GoldStandardBookmarks" }, "Tag" : { "pluralLabel" : "Tags" }, "User" : { "pluralLabel" : "Users" }, "Group" : { "pluralLabel" : "Groups" }, "Sphere" : { "pluralLabel" : "Spheres" } }, "properties" : { "count" : { "valueType" : "number" }, "date" : { "valueType" : "date" }, "changeDate" : { "valueType" : "date" }, "url" : { "valueType" : "url" }, "id" : { "valueType" : "url" }, "tags" : { "valueType" : "item" }, "user" : { "valueType" : "item" } }, "items" : [ { "type" : "Publication", "id" : "https://puma.ub.uni-stuttgart.de/bibtex/2e9294d19b2f705461fe8340bf970a6fb/inspo5", "tags" : [ "Fiber","Lateral","length","mechanics","matrix","heterogeneity","Extracellular","transmission","Endomysial","force","Sarcomere","bundle","connections" ], "intraHash" : "e9294d19b2f705461fe8340bf970a6fb", "interHash" : "7c13ec95eb31404c7683564d78305f64", "label" : "The impact of endomysium integrity on skeletal muscle fiber bundle mechanics", "user" : "inspo5", "description" : "", "date" : "2025-11-05 15:18:13", "changeDate" : "2025-11-05 15:18:13", "count" : 2, "pub-type": "article", "journal": "Journal of Biomechanics","publisher":"Elsevier BV", "year": "2025", "url": "http://dx.doi.org/10.1016/j.jbiomech.2025.112957", "author": [ "Paolo Carlo Danesini","André Tomalka","Tobias Siebert","Filiz Ates" ], "authors": [ {"first" : "Paolo Carlo", "last" : "Danesini"}, {"first" : "André", "last" : "Tomalka"}, {"first" : "Tobias", "last" : "Siebert"}, {"first" : "Filiz", "last" : "Ates"} ], "editor": [ "Tobias Siebert" ], "editors": [ {"first" : "Tobias", "last" : "Siebert"} ], "volume": "192","pages": "112957","abstract": "The endomysium, the innermost layer of the extracellular matrix (ECM), was shown to play an important role in both passive and active force transmission. However, its mechanical contribution within muscle fiber bundles remains incompletely understood. We hypothesized that dissecting one of the endomysial connections within a fiber bundle would alter force production and lead to changes in sarcomere lengths and their heterogeneity. Muscle fiber bundles (n = 12) were extracted from the extensor digitorum longus muscles of rats and chemically skinned. Their passive and active stress-length relationships were measured under two conditions: (i) with intact endomysium and (ii) after blunt dissection of endomysial connections between two adjacent peripheral fibers. Disruption of endomysial continuity significantly reduced passive stress by 26.5 % (p < 0.01) and active stress by 21.9 % (p < 0.001) on average across all lengths tested. It also shifted the optimal fiber length (Lopt) to longer values by 6.2 % (p < 0.01). Despite these mechanical changes, average sarcomere lengths (along fibers) and their heterogeneity remained unchanged. Length heterogeneity was only observed at a longer fiber length (1.3 Lopt) in the passive state before dissection. These findings demonstrate that endomysial connections are integral to the mechanical behavior of muscle fiber bundles, influencing both passive and active stress. The absence of sarcomere length changes along fibers suggests that other microstructural mechanisms, such as altered lattice spacing or impaired lateral force transmission, may underlie the observed changes. These results highlight the importance of ECM integrity in muscle mechanics and have implications for orthopedic interventions and neuromuscular disorder management.", "issn" : "0021-9290", "doi" : "10.1016/j.jbiomech.2025.112957", "bibtexKey": "Danesini_2025" } , { "type" : "Publication", "id" : "https://puma.ub.uni-stuttgart.de/bibtex/2e0eb12714cb5e8c70bc4ef13a3f70c30/inspo5", "tags" : [ "stretch","epression","surae","force","performance","enhancement","reflex","triceps" ], "intraHash" : "e0eb12714cb5e8c70bc4ef13a3f70c30", "interHash" : "40953d65f08f042d8f840b9b2462a29b", "label" : "The stretch\u2013shortening cycle effect is not associated with cortical or spinal excitability modulations", "user" : "inspo5", "description" : "", "date" : "2025-06-20 14:16:43", "changeDate" : "2025-06-20 14:16:43", "count" : 3, "pub-type": "article", "journal": "The Journal of Physiology","publisher":"Wiley", "year": "2025", "url": "http://dx.doi.org/10.1113/JP287508", "author": [ "Lea\u2010Fedia Rissmann","Brent James Raiteri","Wolfgang Seiberl","Tobias Siebert","Daniel Hahn" ], "authors": [ {"first" : "Lea\u2010Fedia", "last" : "Rissmann"}, {"first" : "Brent James", "last" : "Raiteri"}, {"first" : "Wolfgang", "last" : "Seiberl"}, {"first" : "Tobias", "last" : "Siebert"}, {"first" : "Daniel", "last" : "Hahn"} ], "abstract": "It is unclear whether cortical and spinal excitability modulations contribute to enhanced stretch\u2013shortening cycle (SSC) performance. Therefore, this study investigated cortical and spinal excitability modulations during and following shortening of SSC contractions compared with pure shortening (SHO) contractions. Participants (n = 18) performed submaximal voluntary plantar flexion contractions while prone on the dynamometer bench. The right foot was strapped onto the dynamometer's footplate attachment, and the resultant ankle joint torque and crank arm angle were recorded. Cortical and spinal excitability modulations of the soleus muscle were analysed by eliciting compound muscle actional potentials via electrical nerve stimulation, cervicomedullary motor-evoked potentials (CMEPs) via electrical stimulation of the spinal cord, and motor-evoked potentials (MEPs) via magnetic stimulation of the motor cortex. Mean torque following stretch was significantly increased by 7 ± 3% (P = 0.029) compared with the fixed-end reference (REF) contraction, and mean torque during shortening of SSC compared with SHO was significantly increased by 12 ± 24% (P = 0.046). Mean steady-state torque was significantly lower by 13 ± 3% (P = 0.006) and 9 ± 12% (P = 0.011) following SSC compared with REF and SHO, respectively. Mean steady-state torque was not significantly different following SHO compared with REF (7 ± 8%, P = 0.456). CMEPs and MEPs were also not significantly different during shortening of SSC compared with SHO (P ≥ 0.885) or during the steady state of SSC, SHO and REF (P ≥ 0.727). Therefore, our results indicate that SSC performance was not associated with cortical or spinal excitability modulations during or after shortening, but rather driven by mechanical mechanisms triggered during active stretch.", "issn" : "1469-7793", "doi" : "10.1113/jp287508", "bibtexKey": "Rissmann_2025" } , { "type" : "Publication", "id" : "https://puma.ub.uni-stuttgart.de/bibtex/2dd555a4fd35faa41b3f9a475802f1084/inspo5", "tags" : [ "joint","moment","muscle-tendon","dynamics","gearing","locomotion","muscle","sound","ultra","force","enhancement" ], "intraHash" : "dd555a4fd35faa41b3f9a475802f1084", "interHash" : "16909b6df8a0d1c17a291e8e0cb7eaf7", "label" : "Decoupling of muscle-tendon unit and fascicle velocity contributes to the in vivo stretch-shortening cycle effect in the male human triceps surae muscle", "user" : "inspo5", "description" : "", "date" : "2024-12-19 16:12:00", "changeDate" : "2024-12-19 16:12:00", "count" : 2, "pub-type": "article", "journal": "The Physiological Society", "year": "2024", "url": "https://physoc.onlinelibrary.wiley.com/doi/10.14814/phy2.70131", "author": [ "Denis Holzer","Daniel Hahn","Ansgar Schwirtz","Tobias Siebert","Wolfgang Seiberl" ], "authors": [ {"first" : "Denis", "last" : "Holzer"}, {"first" : "Daniel", "last" : "Hahn"}, {"first" : "Ansgar", "last" : "Schwirtz"}, {"first" : "Tobias", "last" : "Siebert"}, {"first" : "Wolfgang", "last" : "Seiberl"} ], "editor": [ "Tobias Siebert" ], "editors": [ {"first" : "Tobias", "last" : "Siebert"} ], "volume": "12","number": "23","pages": "e70131","abstract": "During the shortening of stretch-shortening cycles (SSCs), muscle force output is enhanced compared with pure shortening (SHO), referred to as the SSC-effect. In general, muscle-tendon unit (MTU), muscle belly, muscle fascicle, and tendon length changes can be decoupled during contraction, which affects force generation and elastic recoil. We researched whether MTU decoupling contributes to the SSC-effect. Participants performed electrically stimulated submaximal fixed-end, SSC, and SHO plantar-flexions on a dynamometer at two velocities (40, 120°/s) and two ranges of motion (15, 25°). Fascicle and tendon length changes of the gastrocnemius medialis, and ankle joint kinematics were assessed by ultrasound and motion capture, respectively. During SSC shortening, ankle joint torque and work, MTU force and work, and fascicle force were increased by 12%\u201322% compared with SHO, confirming a SSC-effect. Further, fascicle length change and velocity during SSCs were significantly reduced compared with SHO condition, and SSC fascicle work was decreased by ~35%. Our results indicate that MTU decoupling leads to a reduction in fascicle shortening amplitude and velocity, thereby increasing the muscle's force capacity while reducing its work output during SSC shortening. MTU decoupling therefore contributes to the SSC-effect and underlines the limited transferability of joint work measurements to estimated muscle work.", "language" : "English", "doi" : "10.14814/phy2.70131", "bibtexKey": "holzer2024decoupling" } , { "type" : "Publication", "id" : "https://puma.ub.uni-stuttgart.de/bibtex/283fba02b010557af3f547c378cdb6de6/inspo5", "tags" : [ "fiber","Intramuscular","tissue","matrix","Extracellular","integrity","transmission","Endomysium","Connective","Muscle","force" ], "intraHash" : "83fba02b010557af3f547c378cdb6de6", "interHash" : "2d12b002242e8974ec406082ad65e8b3", "label" : "Endomysium determines active and passive force production in muscle fibers", "user" : "inspo5", "description" : "", "date" : "2024-05-08 11:25:57", "changeDate" : "2024-08-07 11:33:21", "count" : 8, "pub-type": "article", "journal": "Journal of Biomechanics","publisher":"Elsevier BV", "year": "2024", "url": "http://dx.doi.org/10.1016/j.jbiomech.2024.112134", "author": [ "Paolo Carlo Danesini","Maximilian Heim","André Tomalka","Tobias Siebert","Filiz Ates" ], "authors": [ {"first" : "Paolo", "last" : "Carlo Danesini"}, {"first" : "Maximilian", "last" : "Heim"}, {"first" : "André", "last" : "Tomalka"}, {"first" : "Tobias", "last" : "Siebert"}, {"first" : "Filiz", "last" : "Ates"} ], "editor": [ "Tobias Siebert" ], "editors": [ {"first" : "Tobias", "last" : "Siebert"} ], "volume": "168","pages": "112134","abstract": "Connective tissues can be recognized as an important structural support element in muscles. Recent studies have also highlighted its importance in active force generation and transmission between muscles, particularly through the epimysium. In the present study, we aimed to investigate the impact of the endomysium, the connective tissue surrounding muscle fibers, on both passive and active force production. Pairs of skeletal muscle fibers were extracted from the extensor digitorum longus muscles of rats and, after chemical skinning, their passive and active force\u2013length relationships were measured under two conditions: (i) with the endomysium between muscle fibers intact, and (ii) after its dissection. We found that the dissection of the endomysium caused force to significantly decrease in both active (by 22.2 % when normalized to the maximum isometric force; p < 0.001) and passive conditions (by 25.9 % when normalized to the maximum isometric force; p = 0.034). These findings indicate that the absence of endomysium compromises muscle fiber\u2019s not only passive but also active force production. This effect may be attributed to increased heterogeneity in sarcomere lengths, enhanced lattice spacing between myofilaments, or a diminished role of trans-sarcolemmal proteins due to dissecting the endomysium. Future investigations into the underlying mechanisms and their implications for various extracellular matrix-related diseases are warranted.", "language" : "English", "issn" : "0021-9290", "doi" : "10.1016/j.jbiomech.2024.112134", "bibtexKey": "Carlo_Danesini_2024" } , { "type" : "Publication", "id" : "https://puma.ub.uni-stuttgart.de/bibtex/2f3d78410850201349b3420cb0f71115a/inspo5", "tags" : [ "Stomach","Uniaxial","Force","experiments","velocity","length","layer","relationship","muscle","Contractile","Separated","tensile","wall","Organ","properties" ], "intraHash" : "f3d78410850201349b3420cb0f71115a", "interHash" : "b79cfd3a81cd8360cba0a6d4729f7452", "label" : "Influence of layer separation on the determination of stomach smooth muscle properties.", "user" : "inspo5", "description" : "", "date" : "2022-07-19 11:10:29", "changeDate" : "2022-07-19 09:10:56", "count" : 2, "pub-type": "article", "journal": "Pflugers Arch", "year": "2021", "url": "https://link.springer.com/article/10.1007/s00424-021-02568-5", "author": [ "Mischa Borsdorf","Markus Böl","Tobias Siebert" ], "authors": [ {"first" : "Mischa", "last" : "Borsdorf"}, {"first" : "Markus", "last" : "Böl"}, {"first" : "Tobias", "last" : "Siebert"} ], "editor": [ "Tobias Siebert" ], "editors": [ {"first" : "Tobias", "last" : "Siebert"} ], "volume": "473","pages": "911-920","abstract": "Uniaxial tensile experiments are a standard method to determine the contractile properties of smooth muscles. Smooth muscle strips from organs of the urogenital and gastrointestinal tract contain multiple muscle layers with different muscle fiber orientations, which are frequently not separated for the experiments. During strip activation, these muscle fibers contract in deviant orientations from the force-measuring axis, affecting the biomechanical characteristics of the tissue strips. This study aimed to investigate the influence of muscle layer separation on the determination of smooth muscle properties. Smooth muscle strips, consisting of longitudinal and circumferential muscle layers (whole-muscle strips [WMS]), and smooth muscle strips, consisting of only the circumferential muscle layer (separated layer strips [SLS]), have been prepared from the fundus of the porcine stomach. Strips were mounted with muscle fibers of the circumferential layer inline with the force-measuring axis of the uniaxial testing setup. The force\u2013length (FLR) and force\u2013velocity relationships (FVR) were determined through a series of isometric and isotonic contractions, respectively. Muscle layer separation revealed no changes in the FLR. However, the SLS exhibited a higher maximal shortening velocity and a lower curvature factor than WMS. During WMS activation, the transversally oriented muscle fibers of the longitudinal layer shortened, resulting in a narrowing of this layer. Expecting volume constancy of muscle tissue, this narrowing leads to a lengthening of the longitudinal layer, which counteracted the shortening of the circumferential layer during isotonic contractions. Consequently, the shortening velocities of the WMS were decreased significantly. This effect was stronger at high shortening velocities.", "language" : "English", "doi" : "doi:10.1007/s00424-021-02568-5", "bibtexKey": "borsdorf2021influence" } , { "type" : "Publication", "id" : "https://puma.ub.uni-stuttgart.de/bibtex/2c5478835f2cd88ec490ace0e656a5b8f/inspo5", "tags" : [ "gastric","relation","tissue","enhancement","force-velocity","contraction-behavior","muscle","motility","depression","force","smooth","force-length","properties" ], "intraHash" : "c5478835f2cd88ec490ace0e656a5b8f", "interHash" : "a5eeda529640c3525644d1772eb0cba6", "label" : "Porcine Stomach Smooth Muscle Force Depends on History-Effects", "user" : "inspo5", "description" : "", "date" : "2022-07-19 11:10:29", "changeDate" : "2022-07-19 09:14:49", "count" : 2, "pub-type": "article", "journal": "Front Physiol", "year": "2017", "url": "https://www.ncbi.nlm.nih.gov/pubmed/29093684", "author": [ "A. Tomalka","M. Borsdorf","M. Böl","T. Siebert" ], "authors": [ {"first" : "A.", "last" : "Tomalka"}, {"first" : "M.", "last" : "Borsdorf"}, {"first" : "M.", "last" : "Böl"}, {"first" : "T.", "last" : "Siebert"} ], "volume": "8","pages": "802","abstract": "The stomach serves as food reservoir, mixing organ and absorption area for certain substances, while continually varying its position and size. Large dimensional changes during ingestion and gastric emptying of the stomach are associated with large changes in smooth muscle length. These length changes might induce history-effects, namely force depression (FD) following active muscle shortening and force enhancement (FE) following active muscle stretch. Both effects have impact on the force generating capacity of the stomach, and thus functional relevance. However, less is known about history-effects and active smooth muscle properties of stomach smooth muscle. Thus, the aim of this study was to investigate biomechanical muscle properties as force-length and force-velocity relations (FVR) of porcine stomach smooth muscle strips, extended by the analysis of history-effects on smooth muscle force. Therefore, in total n = 54 tissue strips were dissected in longitudinal direction from the ventral fundus of porcine stomachs. Different isometric, isotonic, and isokinetic contraction protocols were performed during electrical muscle stimulation. Cross-sectional areas (CSA) of smooth muscles were determined from cryo-histological sections stained with Picrosirius Red. Results revealed that maximum smooth muscle tension was 10.4 ± 2.6 N/cm2. Maximum shortening velocity (Vmax ) and curvature factor (curv) of the FVR were 0.04 ± 0.01 [optimum muscle length/s] and 0.36 ± 0.15, respectively. The findings of the present study demonstrated significant (P < 0.05) FD [up to 32% maximum muscle force (Fim )] and FE (up to 16% Fim ) of gastric muscle tissue, respectively. The FE- and FD-values increased with increasing ramp amplitude. This outstanding muscle behavior is not accounted for in existing models so far and strongly supports the idea of a holistic reflection of distinct stomach structure and function. For the first time this study provides a comprehensive set of stomach smooth muscle parameters including classic biomechanical muscle properties and history-dependent effects, offering the possibility for the development and validation of computational stomach models. Furthermore, this data set facilitates novel insights in gastric motility and contraction behavior based on the re-evaluation of existing contractile mechanisms. That will likely help to understand physiological functions or dysfunctions in terms of gastric accommodation and emptying.", "issn" : "1664-042X (Print)\r\n1664-042X (Linking)", "doi" : "10.3389/fphys.2017.00802", "bibtexKey": "RN6295" } , { "type" : "Publication", "id" : "https://puma.ub.uni-stuttgart.de/bibtex/25d6577488e95db17ddb2481f80195cc7/inspo5", "tags" : [ "extremities","strength","lower","Bilateral","training","force","unilateral","deficit" ], "intraHash" : "5d6577488e95db17ddb2481f80195cc7", "interHash" : "59d9eee860be3bd4abfe2368da7906d9", "label" : "Correct, fake and absent pre-information does not affect the occurrence and magnitude of the bilateral force deficit", "user" : "inspo5", "description" : "", "date" : "2022-07-19 11:10:29", "changeDate" : "2022-11-03 13:35:45", "count" : 2, "pub-type": "article", "journal": "NIH NLM J Sports Sci Med .", "year": "2014", "url": "https://pubmed.ncbi.nlm.nih.gov/24790502/", "author": [ "Lars Donath","Tobias Siebert","Oliver Faude","Christian Puta" ], "authors": [ {"first" : "Lars", "last" : "Donath"}, {"first" : "Tobias", "last" : "Siebert"}, {"first" : "Oliver", "last" : "Faude"}, {"first" : "Christian", "last" : "Puta"} ], "editor": [ "Tobias Siebert" ], "editors": [ {"first" : "Tobias", "last" : "Siebert"} ], "volume": "1,13","number": "2","pages": "439-443","abstract": "The present study examined whether different pre-information conditions could lead to a volitional modulation of the occurrence and magnitude of the bilateral force deficit (BFD) during isometric leg press. Twenty trained male adults (age: 24.5 ± 1.7 years; weight: 77.5 ± 7.1 kg; height: 1.81 ± 0.05 m) were examined on three days within a week. Isometric leg press was performed on a negatively inclined leg press slide. Each participant completed three maximal isometric strength test sessions with different pre-information conditions given in a graphical chart: no pre-information (NPI; first day), false pre-information (FPI; bilateral force > sum of unilateral forces; second or third day) and correct pre-information (CPI; bilateral force < sum of unilateral forces; second or third day) during bilateral, unilateral-left and unilateral-right leg-press. The sum of left- and right-sided force values were calculated for bilateral (FBL = FBL_left + FBL_right) and unilateral (FUL = FUL_left + FUL_right) analyses. Force data for NPI revealed: Mean (SD): FUL_NPI = 3023 N (435) vs. FBL_NPI = 2812 (453); FPI showed FUL_FPI = 3013 N (459) vs. FBL_FPI = 2843 (446) and the CPI revealed FUL_CPI = 3035 (425) vs. FBL_CPI = 2844 (385). The three (no, false, correct) x 2 (FUL, FBL) rANOVA revealed a high significant main effect of Force (F = 61.82, p < 0.001). No significant main effect of the factor Condition and no significant interaction between Force x Condition was observed. The BFD does not rely on the trueness of the given pre-information (no, false, correct). Cognition-based volitional influences on the BFD on supra-spinal level seem negligible. Key pointsBFD is reliable occurring phenomenonAvailable theoretical knowledge does not affect the BFDAlternating sport should include alternating strength exercises.", "language" : "English", "doi" : "PMID: 24790502 /PMCID: PMC3990902", "bibtexKey": "donath2014correct" } , { "type" : "Publication", "id" : "https://puma.ub.uni-stuttgart.de/bibtex/24295397405bd6b64c87b1b56bab3529b/inspo5", "tags" : [ "ergometer","SSC","potentiation","muscle","motion","capture","concentric","force","enhancement","eccentric" ], "intraHash" : "4295397405bd6b64c87b1b56bab3529b", "interHash" : "0535f924fe995f82ece9301a4bd96aa8", "label" : "10 % Higher Rowing Power Outputs After Flexion-Extension-Cycle Compared to an Isolated Concentric Contraction in Sub-Elite Rowers", "user" : "inspo5", "description" : "", "date" : "2022-07-19 11:10:29", "changeDate" : "2022-07-19 09:10:56", "count" : 2, "pub-type": "article", "journal": "Frontiers in Physiology","publisher":"Frontiers Media SA", "year": "2020", "url": "https://doi.org/10.3389%2Ffphys.2020.00521", "author": [ "Steffen Held","Tobias Siebert","Lars Donath" ], "authors": [ {"first" : "Steffen", "last" : "Held"}, {"first" : "Tobias", "last" : "Siebert"}, {"first" : "Lars", "last" : "Donath"} ], "editor": [ "Tobias Siebert" ], "editors": [ {"first" : "Tobias", "last" : "Siebert"} ], "volume": "11","abstract": "The resulting muscular performance is considered notably higher during a stretch shortening cycle (SSC) compared to an isolated concentric contraction. Thus, the present study examined the occurrence and magnitude of rowing performance enhancement after a flexion\u2013extension cycle (FEC) of the legs compared to both concentric contractions only and isometric pre-contraction. Therefore, 31 sub-elite male rowers (age: 25 ± 6 years, height: 1.90 ± 0.02 m, weight: 91 ± 10 kg, weekly training volume: 11.4 ± 5.3 h/week, rowing experience: 7.1 ± 2.7 years) randomly completed (a) isolated concentric rowing strokes (DRIVE), (b) single FEC-type rowing strokes (SLIDE-DRIVE), and (c) rowing strokes with an isometric pre-contraction (ISO-DRIVE). The resulting rowing power (Prow), leg power (Pleg), and work per stroke (WPS) were recorded using motion-capturing, force, and rotation sensors. Comparison of DRIVE and SLIDE-DRIVE revealed significantly (p < 0.05) higher Prow (+11.8 ± 14.0%), Pleg (+19.6 ± 26.7%), and WPS (+9.9 ± 10.5%) during SLIDE-DRIVE. Compared to ISO-DRIVE, Pleg (+9.8 ± 26.6%) and WPS (+6.1 ± 6.7%) are again significantly (p < 0.05) higher for SLIDE-DRIVE. In conclusion, notably higher work and power outputs (compared to an isolated concentric contraction) during FEC rowing referred to an underlying SSC. Future ultrasound studies should elucidate whether a real SSC on the muscle tendon unit level account for these performance enhancements.", "doi" : "10.3389/fphys.2020.00521", "bibtexKey": "Held_2020" } , { "type" : "Publication", "id" : "https://puma.ub.uni-stuttgart.de/bibtex/2dda7c7842f8b627c739b615bde678e28/inspo5", "tags" : [ "joint","maximum","range","estimation","the","corresponding","muscle","of","Far","angle","working","force","TS","on" ], "intraHash" : "dda7c7842f8b627c739b615bde678e28", "interHash" : "12a4bf98a06f2d283088a3622f5e5b0d", "label" : "Considerations on the human Achilles tendon moment arm for in vivo triceps surae muscle--tendon unit force estimates", "user" : "inspo5", "description" : "", "date" : "2022-07-19 11:10:29", "changeDate" : "2022-07-19 09:10:56", "count" : 2, "pub-type": "article", "journal": "Scientific Reports", "year": "2020", "url": "https://doi.org/10.1038/s41598-020-76625-x", "author": [ "Denis Holzer","Florian Kurt Paternoster","Daniel Hahn","Tobias Siebert","Wolfgang Seiberl" ], "authors": [ {"first" : "Denis", "last" : "Holzer"}, {"first" : "Florian Kurt", "last" : "Paternoster"}, {"first" : "Daniel", "last" : "Hahn"}, {"first" : "Tobias", "last" : "Siebert"}, {"first" : "Wolfgang", "last" : "Seiberl"} ], "volume": "10","number": "1","pages": "19559","abstract": "Moment arm-angle functions (MA-a-functions) are commonly used to estimate in vivo muscle forces in humans. However, different MA-a-functions might not only influence the magnitude of the estimated muscle forces but also change the shape of the muscle's estimated force-angle relationship (F-a-r). Therefore, we investigated the influence of different literature based Achilles tendon MA-a-functions on the triceps surae muscle--tendon unit F-a-r. The individual in vivo triceps torque--angle relationship was determined in 14 participants performing maximum voluntary fixed-end plantarflexion contractions from 18.3°þinspace±þinspace3.2° plantarflexion to 24.2°þinspace±þinspace5.1° dorsiflexion on a dynamometer. The resulting F-a-r were calculated using 15 literature-based in vivo Achilles tendon MA-a-functions. MA-a-functions affected the F-a-r shape and magnitude of estimated peak active triceps muscle--tendon unit force. Depending on the MA-a-function used, the triceps was solely operating on the ascending limb (nþinspace=þinspace2), on the ascending limb and plateau region (nþinspace=þinspace12), or on the ascending limb, plateau region and descending limb of the F-a-r (nþinspace=þinspace1). According to our findings, the estimated triceps muscle--tendon unit forces and the shape of the F-a-r are highly dependent on the MA-a-function used. As these functions are affected by many variables, we recommend using individual Achilles tendon MA-a-functions, ideally accounting for contraction intensity-related changes in moment arm magnitude.", "issn" : "2045-2322", "doi" : "10.1038/s41598-020-76625-x", "bibtexKey": "Holzer2020" } ] }