{"3a7ccf521c5e5277829fcbb5d64f36aainspo5":{"DOI":"10.1016/j.jbiomech.2024.112430","ISBN":"","ISSN":"0021-9290","URL":"http://dx.doi.org/10.1016/j.jbiomech.2024.112430","abstract":"Measurement of hip external rotation strength (ERS) is important for preventive and rehabilitative purposes. ERS can be measured in 3 different positions in the isokinetic dynamometer ISOMED2000. However, it is not clear whether these measurement positions effect ERS nor if these positions are reliable in the ISOMED2000. Hence, the purpose of this study was to compare ERS in these positions, the reliability and the agreement. A cross-sectional design was conducted to compare measurement positions and a test–retest design to assess intra-rater reliability and agreement. Twenty-four healthy, physically active athletes participated in the study. Peak isometric torque was measured in the ISOMED in prone, supine, and side-lying position across two sessions on one day. Differences between positions were evaluated with the Wilcoxon-signed-rank test and cliff’s delta. Reliability was assessed via intraclass correlation. Agreement was determined using the standard error of measurement (SEM), minimal detectable change (MDC), and Bland-Altman analysis (BAA). Results indicated a significant influence of measurement position on ERS (p < 0.001) with high effect sizes (>0.74). Reliability and agreement were high in all positions, but highest for the side-lying position (ICC = 0.90 [0.78, 0.96]; SEM = 0.08; MDC = 0.23; BAA_bias = 3.4 %, BAA_loA = 37 %). There were only poor to moderate correlations between measurement positions. These findings suggest that measurement position significantly affects ERS. Furthermore, the effect varies across individuals indicating that normative values cannot be used interchangeably or be adapted across positions. In diagnostic testing ERS should be measured in the same position, but preferably in the side-lying position.","annote":"","author":[{"family":"Frese","given":"Christina"},{"family":"Siebert","given":"Tobias"},{"family":"Bubeck","given":"Dieter"},{"family":"Astner","given":"Iris"},{"family":"Sitte","given":"Daniel"},{"family":"Alt","given":"Wilfried"}],"citation-label":"Frese_2024","collection-editor":[{"family":"Siebert","given":"Tobias"}],"collection-title":"","container-author":[{"family":"Siebert","given":"Tobias"}],"container-title":"Journal of Biomechanics","documents":[],"edition":"","editor":[{"family":"Siebert","given":"Tobias"}],"event-date":{"date-parts":[["2024","nov"]],"literal":"2024"},"event-place":"","id":"3a7ccf521c5e5277829fcbb5d64f36aainspo5","interhash":"f721bdecfed9474b680e050e71e7cc7d","intrahash":"3a7ccf521c5e5277829fcbb5d64f36aa","issue":"","issued":{"date-parts":[["2024","nov"]],"literal":"2024"},"keyword":"Absolute Agreement Dynamometer Hip Within-day reliability strength","misc":{"issn":"0021-9290","doi":"10.1016/j.jbiomech.2024.112430"},"note":"","number":"","page":"112430","page-first":"112430","publisher":"Elsevier BV","publisher-place":"","status":"","title":"Peak hip external rotation torque and single-rater reliability is influenced by measurement position in the ISOMED2000","type":"article-journal","username":"inspo5","version":"","volume":""},"2af41d00232e2b7ff14070cdc783d6e8siemannherzberg":{"DOI":"10.1016/j.ab.2009.11.025","ISBN":"","ISSN":"0003-2697","URL":"https://doi.org/10.1016/j.ab.2009.11.025","abstract":"Current messenger RNA (mRNA) quantification methods are sophisticated\n   tools for the analysis of gene regulation. However, these methods are\n   not suitable for more complex quantitative approaches such as the\n   mathematical modeling of the in vivo regulation of transcription where\n   dynamic cytosolic mRNA concentrations need to be taken into\n   consideration. In the current study, the ``standard curve method'' for\n   quantitative reverse transcription real-time polymerase chain reaction\n   (qRT-PCR) was extended by including an internal RNA standard. This\n   standard enables transcript losses that occur during the process, as\n   well as variations resulting from nonquantitative processes, to be\n   accounted for. The use of an internal standard yielded transcript\n   concentration estimates that were on average seven times higher than\n   those in cases where an internal standard is omitted. Choosing the cra\n   modulon in Escherichia coli as an example, the method applied shows that\n   the regulation of the Cra protein, as well as the growth rate-dependent\n   regulation, need to be taken into consideration. The new method, which\n   enables the determination of cytosolic mRNA concentrations, allows the\n   quantitative representation of transcriptional dynamics. This is an\n   important aspect of the analysis of the complex interactions of\n   metabolism and regulation and in the application of mathematical\n   modeling for systems biology. (C) 2009 Elsevier Inc. All rights\n   reserved.","annote":"","author":[{"family":"Schuhmacher","given":"Tom"},{"family":"Lemuth","given":"Karin"},{"family":"Hardiman","given":"Timo"},{"family":"Vacun","given":"Gabi"},{"family":"Reuss","given":"Matthias"},{"family":"Siemann-Herzberg","given":"Martin"}],"citation-label":"ISI:000274615100010","collection-editor":[],"collection-title":"","container-author":[],"container-title":"ANALYTICAL BIOCHEMISTRY","documents":[],"edition":"","editor":[],"event-date":{"date-parts":[["{2010}","MAR 15"]],"literal":"{2010}"},"event-place":"525 B ST, STE 1900, SAN DIEGO, CA 92101-4495 USA","id":"2af41d00232e2b7ff14070cdc783d6e8siemannherzberg","interhash":"84c2f964d514c704ed8241b609338635","intrahash":"2af41d00232e2b7ff14070cdc783d6e8","issue":"2","issued":{"date-parts":[["{2010}","MAR 15"]],"literal":"{2010}"},"keyword":"Absolute Gene Internal concentrations; expression} mRNA myown qRT-PCR; quantification; standard; {Cytosolic","misc":{"issn":"{0003-2697}","research-areas":"{Biochemistry \\& Molecular Biology; Chemistry}","doc-delivery-number":"{556TK}","usage-count-since-2013":"{9}","affiliation":"{Siemann-Herzberg, M (Reprint Author), Univ Stuttgart, Inst Biochem Engn, D-70569 Stuttgart, Germany.\n   Schuhmacher, Tom; Lemuth, Karin; Hardiman, Timo; Vacun, Gabi; Reuss, Matthias; Siemann-Herzberg, Martin, Univ Stuttgart, Inst Biochem Engn, D-70569 Stuttgart, Germany.}","web-of-science-categories":"{Biochemical Research Methods; Biochemistry \\& Molecular Biology;\n   Chemistry, Analytical}","journal-iso":"{Anal. Biochem.}","da":"{2018-01-25}","author-email":"{siemann@ibvt.uni-stuttgart.de}","keywords-plus":"{SANDWICH-HYBRIDIZATION ASSAY; REGULATORY PROTEIN; GENE-EXPRESSION;\n   RT-PCR; QUANTIFICATION; MICROARRAY; BINDING; FRUR; TRANSCRIPTION; COPY}","number-of-cited-references":"{43}","language":"{English}","unique-id":"{ISI:000274615100010}","usage-count-last-180-days":"{0}","doi":"{10.1016/j.ab.2009.11.025}","times-cited":"{6}"},"note":"","number":"2","number-of-pages":"5","page":"212-217","page-first":"212","publisher":"ACADEMIC PRESS INC ELSEVIER SCIENCE","publisher-place":"525 B ST, STE 1900, SAN DIEGO, CA 92101-4495 USA","status":"","title":"Quantifying cytosolic messenger RNA concentrations in Escherichia coli\n   using real-time polymerase chain reaction for a systems biology approach","type":"article-journal","username":"siemannherzberg","version":"","volume":"398"},"dccb0302d8b765b1450e86f4b2798951amerwafai":{"DOI":"","ISBN":"","ISSN":"","URL":"","abstract":"We provide details on the shared-memory parallelization for manycore architectures of the molecular dynamics framework ls1-mardyn, including an optimization of the SIMD vectorization for multi-centered molecules. The novel shared-memory parallelization scheme allows to re- tain Newton's third law optimization and exhibits very good scaling on many-core devices such as a full Xeon Phi card running 240 threads. The Xeon Phi can thus be exploited and delivers comparable performance as IvyBridge nodes in our experiments.","annote":"","author":[{"family":"Tchipev","given":"Nikola"},{"family":"Wafai","given":"Amer"},{"family":"Glass","given":"Colin W."},{"family":"Eckhardt","given":"Wolfgang"},{"family":"Heinecke","given":"Alexander"},{"family":"Bungartz","given":"Hans-Joachim"},{"family":"Neumann","given":"Philipp"}],"citation-label":"wafai15","collection-editor":[{"family":"Träff","given":"Jesper Larsson"},{"family":"Hunold","given":"Sascha"},{"family":"Versaci","given":"Francesco"}],"collection-title":"LNCS","container-author":[{"family":"Träff","given":"Jesper Larsson"},{"family":"Hunold","given":"Sascha"},{"family":"Versaci","given":"Francesco"}],"container-title":"Euro-Par 2015: Parallel Processing","documents":[],"edition":"","editor":[{"family":"Träff","given":"Jesper Larsson"},{"family":"Hunold","given":"Sascha"},{"family":"Versaci","given":"Francesco"}],"event-date":{"date-parts":[["2015","August"]],"literal":"2015"},"event-place":"Vienna, Austria","id":"dccb0302d8b765b1450e86f4b2798951amerwafai","interhash":"902fd5f88d25cf9f9a271091a6bbd41a","intrahash":"dccb0302d8b765b1450e86f4b2798951","issue":"","issued":{"date-parts":[["2015","August"]],"literal":"2015"},"keyword":"HLRS SCOPE absolute and calculation cell colored core distributed dynamic force gather intel interaction law linked memory molecular myown newton operation optimization parallel parallelization performance phi processing range scatter shared short site third xeon yellow","misc":{"date-added":"2015-08-19 09:05:42 +0000","date-modified":"2015-08-19 09:10:27 +0000"},"note":"","number":"","page":"","page-first":"","publisher":"","publisher-place":"Vienna, Austria","status":"","title":"Optimized Force Calculation of Molecular Dynamics Simulations for the Intel Xeon Phi","type":"paper-conference","username":"amerwafai","version":"","volume":"9233"}}