L-valine production during growth of pyruvate dehydrogenase complex-deficient Corynebacterium glutamicum in the presence of ethanol or by inactivation of the transcriptional regulator SugR
B. Blombach, A. Arndt, M. Auchter, und B. Eikmanns.
Appl. Environ. Microbiol. 75 (4): 1197--1200 (Februar 2009)

Pyruvate dehydrogenase complex-deficient strains of Corynebacterium glutamicum produce L-valine from glucose only after depletion of the acetate required for growth. Here we show that inactivation of the DeoR-type transcriptional regulator SugR or replacement of acetate by ethanol already in course of the growth phase results in efficient L-valine production.

DOI

10.1128/AEM.02351-08

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@article{blombach_l-valine_2009,
  abstract = {Pyruvate dehydrogenase complex-deficient strains of Corynebacterium glutamicum produce L-valine from glucose only after depletion of the acetate required for growth. Here we show that inactivation of the DeoR-type transcriptional regulator SugR or replacement of acetate by ethanol already in course of the growth phase results in efficient L-valine production.},
  added-at = {2018-02-09T13:18:17.000+0100},
  author = {Blombach, Bastian and Arndt, Annette and Auchter, Marc and Eikmanns, Bernhard J.},
  biburl = {https://puma.ub.uni-stuttgart.de/bibtex/205af8a7b28d60ba8272685f0427eaadb/bastian},
  doi = {10.1128/AEM.02351-08},
  interhash = {581b084966b1a19b10f06b5ed069aa58},
  intrahash = {05af8a7b28d60ba8272685f0427eaadb},
  issn = {1098-5336},
  journal = {Appl. Environ. Microbiol.},
  keywords = {Complex Corynebacterium Dehydrogenase Ethanol, Factors, Gene Knockout Pyruvate Techniques, Transcription Valine, glutamicum, myown},
  language = {eng},
  month = feb,
  number = 4,
  pages = {1197--1200},
  pmcid = {PMC2643581},
  pmid = {19088318},
  timestamp = {2018-02-09T13:18:56.000+0100},
  title = {L-valine production during growth of pyruvate dehydrogenase complex-deficient {Corynebacterium} glutamicum in the presence of ethanol or by inactivation of the transcriptional regulator {SugR}},
  volume = 75,
  year = 2009
}

%0 Journal Article
%1 blombach_l-valine_2009
%A Blombach, Bastian
%A Arndt, Annette
%A Auchter, Marc
%A Eikmanns, Bernhard J.
%D 2009
%J Appl. Environ. Microbiol.
%K Complex Corynebacterium Dehydrogenase Ethanol, Factors, Gene Knockout Pyruvate Techniques, Transcription Valine, glutamicum, myown
%N 4
%P 1197--1200
%R 10.1128/AEM.02351-08
%T L-valine production during growth of pyruvate dehydrogenase complex-deficient Corynebacterium glutamicum in the presence of ethanol or by inactivation of the transcriptional regulator SugR
%V 75
%X Pyruvate dehydrogenase complex-deficient strains of Corynebacterium glutamicum produce L-valine from glucose only after depletion of the acetate required for growth. Here we show that inactivation of the DeoR-type transcriptional regulator SugR or replacement of acetate by ethanol already in course of the growth phase results in efficient L-valine production.

PUMA

L-valine production during growth of pyruvate dehydrogenase complex-deficient Corynebacterium glutamicum in the presence of ethanol or by inactivation of the transcriptional regulator SugR
B. Blombach, A. Arndt, M. Auchter, und B. Eikmanns.
Appl. Environ. Microbiol. 75 (4): 1197--1200 (Februar 2009)

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