%0 Journal Article %1 blombach_l-valine_2009 %A Blombach, Bastian %A Arndt, Annette %A Auchter, Marc %A Eikmanns, Bernhard J. %D 2009 %J Appl. Environ. Microbiol. %K Complex Corynebacterium Dehydrogenase Ethanol, Factors, Gene Knockout Pyruvate Techniques, Transcription Valine, glutamicum, myown %N 4 %P 1197--1200 %R 10.1128/AEM.02351-08 %T L-valine production during growth of pyruvate dehydrogenase complex-deficient Corynebacterium glutamicum in the presence of ethanol or by inactivation of the transcriptional regulator SugR %V 75 %X Pyruvate dehydrogenase complex-deficient strains of Corynebacterium glutamicum produce L-valine from glucose only after depletion of the acetate required for growth. Here we show that inactivation of the DeoR-type transcriptional regulator SugR or replacement of acetate by ethanol already in course of the growth phase results in efficient L-valine production.

@article{blombach_l-valine_2009, abstract = {Pyruvate dehydrogenase complex-deficient strains of Corynebacterium glutamicum produce L-valine from glucose only after depletion of the acetate required for growth. Here we show that inactivation of the DeoR-type transcriptional regulator SugR or replacement of acetate by ethanol already in course of the growth phase results in efficient L-valine production.}, added-at = {2018-02-09T13:18:17.000+0100}, author = {Blombach, Bastian and Arndt, Annette and Auchter, Marc and Eikmanns, Bernhard J.}, biburl = {https://puma.ub.uni-stuttgart.de/bibtex/205af8a7b28d60ba8272685f0427eaadb/bastian}, doi = {10.1128/AEM.02351-08}, interhash = {581b084966b1a19b10f06b5ed069aa58}, intrahash = {05af8a7b28d60ba8272685f0427eaadb}, issn = {1098-5336}, journal = {Appl. Environ. Microbiol.}, keywords = {Complex Corynebacterium Dehydrogenase Ethanol, Factors, Gene Knockout Pyruvate Techniques, Transcription Valine, glutamicum, myown}, language = {eng}, month = feb, number = 4, pages = {1197--1200}, pmcid = {PMC2643581}, pmid = {19088318}, timestamp = {2018-02-09T13:18:56.000+0100}, title = {L-valine production during growth of pyruvate dehydrogenase complex-deficient {Corynebacterium} glutamicum in the presence of ethanol or by inactivation of the transcriptional regulator {SugR}}, volume = 75, year = 2009 }