Sampling-based Bayesian approaches reveal the importance of quasi-bistable behavior in cellular decision processes on the example of the MAPK signaling pathway in PC-12 cell lines
Positive and negative feedback loops are ubiquitous motifs in biochemical signaling pathways. The mitogen-activated protein kinase (MAPK) pathway module is part of many distinct signaling networks and comprises several of these motifs, whose functioning depends on the cell line at hand and on the particular context.
%0 Journal Article
%1 jensch2017samplingbased
%A Jensch, Antje
%A Thomaseth, Caterina
%A Radde, Nicole E.
%D 2017
%J BMC Systems Biology
%K 2017 access fonds oa open stuttgart uni
%N 1
%P 11
%R 10.1186/s12918-017-0392-6
%T Sampling-based Bayesian approaches reveal the importance of quasi-bistable behavior in cellular decision processes on the example of the MAPK signaling pathway in PC-12 cell lines
%U https://doi.org/10.1186/s12918-017-0392-6
%V 11
%X Positive and negative feedback loops are ubiquitous motifs in biochemical signaling pathways. The mitogen-activated protein kinase (MAPK) pathway module is part of many distinct signaling networks and comprises several of these motifs, whose functioning depends on the cell line at hand and on the particular context.
@article{jensch2017samplingbased,
abstract = {Positive and negative feedback loops are ubiquitous motifs in biochemical signaling pathways. The mitogen-activated protein kinase (MAPK) pathway module is part of many distinct signaling networks and comprises several of these motifs, whose functioning depends on the cell line at hand and on the particular context.},
added-at = {2018-04-22T15:18:29.000+0200},
author = {Jensch, Antje and Thomaseth, Caterina and Radde, Nicole E.},
biburl = {https://puma.ub.uni-stuttgart.de/bibtex/2d1e79db64bab9ea3428bcab755f1d804/droessler},
day = 25,
doi = {10.1186/s12918-017-0392-6},
interhash = {31c4a4aba47f721e52989e479fd49e5c},
intrahash = {d1e79db64bab9ea3428bcab755f1d804},
issn = {1752-0509},
journal = {BMC Systems Biology},
keywords = {2017 access fonds oa open stuttgart uni},
month = jan,
number = 1,
pages = 11,
timestamp = {2018-04-22T13:18:29.000+0200},
title = {Sampling-based Bayesian approaches reveal the importance of quasi-bistable behavior in cellular decision processes on the example of the MAPK signaling pathway in PC-12 cell lines},
url = {https://doi.org/10.1186/s12918-017-0392-6},
volume = 11,
year = 2017
}