Systems biology is attracting significant interest finding applications
not only in pharmaceutical development but also for basic studies on
microbial systems. The latter often concentrate on the quantitative
understanding of global regulation phenomena. So far. these activities
are dominated by academic groups basically mirroring the necessity to
prepare the sound scientific understanding first, before industrial
applications can be derived later. However, this short-term view may not
be sufficient because systems biology already offers numerous benefits
for industrial applications, provided that special constraints are
considered. This contribution indicates some of the constraints worth
noticing when industrial systems biology projects are carried out.
Consequently, differences in project structure and goals between purely
academic and industrial systems biology projects are outlined. (c) 2007
Elsevier B.V All rights reserved.
%0 Journal Article
%1 ISI:000246097000003
%A Takors, R.
%A Bathe, B.
%A Rieping, M.
%A Hans, S.
%A Kelle, R.
%A Huthmacher, K.
%C PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
%D 2007
%I ELSEVIER SCIENCE BV
%J JOURNAL OF BIOTECHNOLOGY
%K myown
%N 2
%P 181-190
%R 10.1016/j.jbiotec.2007.01.031
%T Systems biology for industrial strains and fermentation processes -
Example: Amino acids
%U https://doi.org/10.1016/j.jbiotec.2007.01.031
%V 129
%X Systems biology is attracting significant interest finding applications
not only in pharmaceutical development but also for basic studies on
microbial systems. The latter often concentrate on the quantitative
understanding of global regulation phenomena. So far. these activities
are dominated by academic groups basically mirroring the necessity to
prepare the sound scientific understanding first, before industrial
applications can be derived later. However, this short-term view may not
be sufficient because systems biology already offers numerous benefits
for industrial applications, provided that special constraints are
considered. This contribution indicates some of the constraints worth
noticing when industrial systems biology projects are carried out.
Consequently, differences in project structure and goals between purely
academic and industrial systems biology projects are outlined. (c) 2007
Elsevier B.V All rights reserved.
@article{ISI:000246097000003,
abstract = {{Systems biology is attracting significant interest finding applications
not only in pharmaceutical development but also for basic studies on
microbial systems. The latter often concentrate on the quantitative
understanding of global regulation phenomena. So far. these activities
are dominated by academic groups basically mirroring the necessity to
prepare the sound scientific understanding first, before industrial
applications can be derived later. However, this short-term view may not
be sufficient because systems biology already offers numerous benefits
for industrial applications, provided that special constraints are
considered. This contribution indicates some of the constraints worth
noticing when industrial systems biology projects are carried out.
Consequently, differences in project structure and goals between purely
academic and industrial systems biology projects are outlined. (c) 2007
Elsevier B.V All rights reserved.}},
added-at = {2018-06-08T11:30:15.000+0200},
address = {{PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS}},
affiliation = {{Takors, R (Reprint Author), Degussa GmbH, Kantstr 2, D-33790 Halle, Germany.
Degussa GmbH, D-33790 Halle, Germany.}},
author = {Takors, R. and Bathe, B. and Rieping, M. and Hans, S. and Kelle, R. and Huthmacher, K.},
author-email = {{ralf.takors@degussa.com}},
biburl = {https://puma.ub.uni-stuttgart.de/bibtex/2c3450b07960505a187ab1abb665fefe5/ralftakors},
da = {{2018-01-26}},
doc-delivery-number = {{162OK}},
doi = {{10.1016/j.jbiotec.2007.01.031}},
interhash = {80c7e4885e80067fdd9db4f946c9a328},
intrahash = {c3450b07960505a187ab1abb665fefe5},
issn = {{0168-1656}},
journal = {{JOURNAL OF BIOTECHNOLOGY}},
journal-iso = {{J. Biotechnol.}},
keywords = {myown},
keywords-plus = {{METABOLIC-FLUX ANALYSIS; SENSOR REACTOR APPROACH; L-LYSINE PRODUCTION;
IN-VIVO KINETICS; SACCHAROMYCES-CEREVISIAE; LABELING EXPERIMENTS;
FUNCTIONAL GENOMICS; ESCHERICHIA-COLI; DYNAMICS; SEQUENCE}},
language = {{English}},
month = {{APR 30}},
note = {{International Workshop on Molecular Systems Biology, Bielefeld Univ, Bielefeld, GERMANY, JUN, 2006}},
number = {{2}},
number-of-cited-references = {{51}},
pages = {{181-190}},
publisher = {{ELSEVIER SCIENCE BV}},
research-areas = {{Biotechnology \& Applied Microbiology}},
times-cited = {{67}},
timestamp = {2018-06-08T09:30:15.000+0200},
title = {{Systems biology for industrial strains and fermentation processes -
Example: Amino acids}},
type = {{Article; Proceedings Paper}},
unique-id = {{ISI:000246097000003}},
url = {https://doi.org/10.1016/j.jbiotec.2007.01.031},
usage-count-last-180-days = {{0}},
usage-count-since-2013 = {{18}},
volume = {{129}},
web-of-science-categories = {{Biotechnology \& Applied Microbiology}},
year = {{2007}}
}